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Citicoline (CDP-Choline) is a powerful neuro-nutrient that serves as a precursor to Acetylcholine, the brain’s primary chemical for learning and memory. IV Therapy delivers this molecule directly to your brain cells to enhance focus, repair damage, and clear brain fog.
In the world of Biohacking and Nootropics, Citicoline is revered for its safety and efficacy. Whether you are a CEO needing sharper focus or a patient recovering from a neurological event, Specialist Dr. Ömer Fatih Şahin administers this therapy to optimize your brain health.
How Does It Work?
It works like a comprehensive optimization process for brain function.
1. Boosts Acetylcholine: Increases the neurotransmitter responsible for processing information and memory recall.
2. Repairs Neurons: It helps rebuild the cell membranes (phospholipids) of neurons, essentially repairing the “hardware” of your brain.
3. Increases Blood Flow: Enhances cerebral circulation, delivering more oxygen to the brain.
Who is it For ?
● The High Performer: Executives, developers, and students who need sustained attention without the jitters of caffeine.
● Post-COVID Brain Fog: For those struggling to find words or feeling mentally “cloudy.”
● Stroke Recovery: Clinically proven to support recovery in the acute and chronic phases of ischemic stroke.
● Glaucoma Patients: Helps protect the optic nerve from damage, offering a neuroprotective shield for your vision.
● Seniors: To fight age-related memory decline.
IV vs. Oral Supplements
Why choose the IV route?
● Bioavailability: When you take Citicoline orally, it must be metabolized by the liver. IV delivery ensures 100% of the dose enters circulation and reaches the brain tissue rapidly.
● Therapeutic Dosing: We can administer higher, clinically effective doses safely via IV that would be difficult to ingest orally. Oral administration can be continued after IV treatment.

Frequently Asked Questions (FAQ)
● Question: Will it make me anxious like too much coffee?
● Answer: No. Unlike stimulants (caffeine/amphetamines) that force the brain to race,
Citicoline provides energy by nourishing the brain. The result is a state of “Calm
Focus”—you are alert but relaxed.
● Question: I am recovering from a Stroke. Is it too late?
● Answer: It is best when started early (acute/subacute phase). However, it is also
beneficial in the chronic phase to support neuroplasticity (the brain’s ability to rewire
itself).
● Question: Can it help with Glaucoma?
● Answer: Yes. Citicoline is one of the few neuroprotective agents proven to help
preserve the optic nerve in glaucoma patients. It is an excellent complementary
therapy to your eye drops.
● Question: Is it safe?
● Answer: Citicoline is a naturally occurring compound in the body with an excellent
safety profile. It is non-toxic and well-tolerated.
● Question: What is the price?
● Answer: Pricing depends on the dosage (mg) and the number of sessions in your
package. Please contact us for a personalized quote.
Book Your Brain Boost
To sharpen your mind and protect your brain health, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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Sculptra is an FDA-approved biostimulator treatment that activates your skin’s natural power to produce collagen, restoring facial volume and improving skin quality for up to 2 years. Unlike traditional fillers, it offers gradual, natural-looking results without the “puffy” look. At our clinic in Nişantaşı, Istanbul, we offer premium Sculptra treatments tailored for international patients seeking world-class aesthetic care.
What is Sculptra?
● Sculptra is an injectable collagen-stimulating treatment formulated with PLLA. It works deep within the dermis to help revitalize collagen production and restore your skin’s inner structure. It is the ideal choice for patients who want to treat the underlying cause of facial aging rather than just the symptoms.
How Does It Work?
Sculptra does not just “fill” a wrinkle; it rebuilds the skin matrix.
1. Stimulation: PLLA microparticles are delivered into the skin to activate collagen production.
2. Collagen Growth: These particles stimulate fibroblasts to produce new collagen strands.
3. Restoration: Over time (4-6 weeks), the skin becomes firmer, thicker, and more youthful.
🧪 Scientific Fact: Clinical studies show that Sculptra can increase Type-1 Collagen levels by 66.5% after just 3 months. This makes it a powerful anti-aging foundation for your skin.
Why Choose Sculptra in Istanbul?
Many international patients choose Istanbul for Sculptra treatments due to:
● High-Quality Care: Treatment by experienced medical doctors using FDA-approved products.
● Cost-Effectiveness: Premium aesthetic treatments at competitive prices compared to Europe or the US.
● Location: Our clinic is located in Nişantaşı, the luxury fashion and medical district of Istanbul, perfect for a combined medical & leisure trip.
Sculptra vs. Hyaluronic Acid Fillers
It is important to understand the difference to choose the right treatment for your needs:
● Hyaluronic Acid (HA) Fillers: Provide immediate volume. They are gels that fill space. Best for specific contouring (lips, nose). Results last 6–18 months.
● Sculptra: Provides gradual, natural restoration. It is a collagen stimulator. Results appear over weeks and last 24+ months. Best for overall skin tightening and natural rejuvenation.
The Procedure & Recovery
The procedure is quick, taking only 30-45 minutes, making it a perfect “lunchtime procedure” that won’t disrupt your holiday.
● Downtime: Minimal. You can return to exploring Istanbul immediately.
● The “5-5-5” Rule: You must massage the treated area for 5 minutes, 5 times a day, for 5 days. This is crucial for distributing the product evenly.
● Restrictions: Avoid saunas, Turkish hamams, and direct prolonged sun exposure for the first 24-48 hours. Flying home the next day is generally safe.
Frequently Asked Questions (FAQ)
What happens if a patient is not satisfied with the results of Sculptra? No, unlike HA fillers,
Sculptra cannot be dissolved immediately with an enzyme. Because it builds your own collagen, the
results are very natural, but this makes it essential to choose an experienced doctor for the
application.
How many sessions do I need? For optimal results, we typically recommend 2 to 3 sessions,
spaced 4-6 weeks apart. However, even a single session provides significant collagen stimulation.
Can I fly after Sculptra? Yes, it is safe to fly after the procedure. We recommend staying hydrated
and avoiding alcohol on your flight to minimize swelling.
Is Sculptra safe? Yes, Sculptra is FDA-approved and has been used safely worldwide since 1999. It
is biocompatible and biodegradable.
When will I see the results? Sculptra is a marathon, not a sprint. You will see a “Sculptra Glow”
starting around week 6, with full results maturing over 3-6 months.

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Sanakin is an advanced biological therapy that processes your own blood to stop scalp micro-inflammation and stimulate hair follicles. It is widely regarded as the premium upgrade to traditional PRP, specifically designed for hair loss prevention and post-transplant result
optimization. Hair loss is not just about genetics; it is often driven by silent inflammation around the hair root. Sanakin creates a serum rich in IL-1Ra, a protein that neutralizes this inflammation, allowing the hair to breathe, feed, and grow again.
Why is it Critical for Hair Transplant Patients? 
If you have had a hair transplant, the real
results start appearing after the healing process. Sanakin is the perfect booster for this specific phase.
● Timing is Key (Month 3 Strategy): We do not recommend injections immediately after surgery to avoid traumatizing the newly planted grafts. The ideal time to start is the 3rd month.
● Boosts New Growth: Around month 3, the “shock loss” phase ends, and permanent hair begins to emerge. Sanakin ensures these new hairs grow thick and strong rather than weak and wispy.
● Scalp Health: It improves blood circulation in the recipient area, ensuring the soil is fertile for your new hair.
Who Else Can Benefit?
● Early Stage Hair Loss: Men and women noticing thinning hair but not yet ready for surgery.
● Itchy/Unhealthy Scalp: Patients suffering from Seborrheic Dermatitis or chronic scalp irritation. Sanakin calms the skin, creating a healthy environment for hair growth.
Sanakin vs. PRP: Which is Better for Hair?
● PRP is excellent for stimulation.
● Sanakin is superior because it stimulates and protects. By stopping the inflammation that
attacks the hair root, it offers a more comprehensive solution for aggressive hair loss.
The Process
1. Blood Draw: We collect a small amount of blood.
2. 3-Hour Incubation: Your blood is incubated to multiply the healing proteins. (You can explore Nişantaşı during this time).
3. Injection: The serum is injected into the scalp using micro-needles.
Frequently Asked Questions (FAQ)
Question: Will it grow hair on a bald head?
Answer: No. Like all non-surgical treatments, it
requires living hair follicles to work. It thickens thin hair and wakes up dormant follicles, but it cannot
create hair where the root is gone.
Question: Can I combine it with my Hair Transplant? 
Answer: Yes, but timing matters. We advise
waiting until the 3rd month after your surgery. This allows the scalp to fully heal and the grafts to
settle. Injecting too early can disturb the new grafts.
Question: Is it painful? 
Answer: We use the finest needles available and local anesthetic sprays to
minimize discomfort. It is generally very well tolerated.
Question: How many sessions? 
Answer: For best results, we recommend a protocol of 3 sessions,
spaced 3-4 weeks apart.

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Sanakin represents a breakthrough in the non-surgical treatment of Knee Osteoarthritis and chronic joint pain. By processing your own blood to multiply anti-inflammatory proteins, we create a powerful serum that stops pain and protects cartilage without chemicals. For patients who want to avoid knee replacement surgery or are wary of the side effects of steroid injections, Sanakin offers a potent, biological alternative. At our clinic, Specialist Dr. Ömer Fatih Şahin applies this German technology with the precision of a pain management expert.
Why Sanakin instead of PRP for Knees?
Standard PRP is great for repair, but it struggles if there is severe inflammation in the joint.
● The Problem: Inflammation (swelling/heat) eats away at your cartilage and causes pain.
● The Solution (Sanakin): It contains high concentrations of IL-1Ra, a protein that specifically blocks the inflammation receptors. It effectively “puts out the fire” inside your knee, creating a safe environment for healing.
Who is the Ideal Candidate?
● Knee Osteoarthritis: Patients experiencing stiffness, pain while climbing stairs, or “loss of
fluid” (Stages 1-3).
● Meniscus Tears: To manage pain and promote healing in degenerative tears.
● Athletes: For rapid recovery from runner’s knee or ligament strains.
● Anti-Cortisone Patients: Those looking for a 100% natural, drug-free pain relief method.
The Process: How it Works
1. Blood Draw: We take blood into special Sanakin tubes.
2. 3-Hour Incubation: Your blood is kept at body temperature. During this time, your cells produce the healing serum. (Perfect time for a lunch or shopping break in Nişantaşı).
3. Injection: The serum is injected into the knee joint painlessly.
Frequently Asked Questions (FAQ)
● Question: Is it better than Cortisone shots?
● Answer: In terms of safety and long-term health, Yes. Cortisone stops pain quickly
but can damage cartilage over time. Sanakin stops pain naturally and protects the
cartilage from further degeneration. It has no side effects.
● Question: Can it prevent surgery?
● Answer: In mild to moderate cases of arthritis, it can significantly delay or even
eliminate the need for knee replacement surgery by preserving joint health.
● Question: Does the injection hurt?
● Answer: Dr. Şahin is an Anesthesiologist. He uses advanced techniques to ensure
the knee injection is virtually painless. There is no need for post-treatment
observation, and patients can depart immediately.

● Question: How many sessions do I need?
● Answer: Typically, a series of 1 to 3 injections is recommended depending on the
severity of your pain.
● Question: Can I combine it with Hyaluronic Acid (Gel)? Answer: Yes, this is a powerful
combination, but timing is key. We use a staged protocol: First, we use Sanakin to stop the
active inflammation (the fire) in the joint. Then, about 3 weeks later, we inject Hyaluronic Acid
to lubricate the joint. This ensures the gel works better in a healthy, inflammation-free
environment.
Book Your Knee Relief
To find out if Sanakin is the right biological treatment for your knees, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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Sanakin is a revolutionary biological treatment that uses your own blood to create a serum rich in anti-inflammatory proteins. It is designed to calm sensitive skin, treat Rosacea, and reverse the signs of aging caused by chronic inflammation. In modern dermatology, we know that aging is largely driven by silent inflammation (Inflammaging). Unlike fillers that just hide the problem, Sanakin stops this inflammation at the cellular level, restoring a healthy, youthful glow.
Why Sanakin over a Vampire Facial (PRP)?
Standard PRP is good, but Sanakin is Smart.
● The Difference: By incubating your blood for 3 hours, Sanakin multiplies the production of Anti-Inflammatory Cytokines.
● The Benefit: While PRP stimulates stimulation, Sanakin provides “Calm Regeneration.” This makes it far superior for patients with sensitive skin, redness, or active acne, where PRP might be too aggressive.
What Does It Treat?
● Rosacea & Chronic Redness: It is one of the few treatments that can calm the “fire” of Rosacea without the heat of lasers.
● Anti-Aging: Improves skin elasticity, reduces fine lines, and tightens pores.
● Acne & Scars: Helps dry out active inflammation and speeds up the healing of acne scars.
● Dark Circles: Improves circulation around the delicate eye area.
The Process: Quality Takes Time
1. Blood Draw: We collect your blood in specialized tubes.
2. 3-Hour Bio-Manufacturing: Your blood is placed in an incubator. This is the magic step where your cells produce the healing serum. (A perfect break to enjoy Istanbul/Nişantaşı).
3. Application: The golden serum is injected into the face, neck, or décolletage using micro-needles.
Frequently Asked Questions (FAQ)
● Question: Is it a filler?
● Answer: No. It does not change your facial shape or freeze your muscles like Botox.
It improves the quality of your skin naturally.
● Question: Is it safe for sensitive skin?
● Answer: Yes, it is the safest option. Since it is 100% autologous (your own blood)
and focuses on reducing inflammation, it is perfect for skin that reacts badly to
chemical peels or lasers.
● Question: How many sessions?
● Answer: We typically recommend a protocol of 3 sessions, spaced 2-3 weeks apart.
● Question: Can I combine it with other treatments?
● Answer: Yes. For total rejuvenation, we often combine Sanakin (to improve skin
quality) with Botox (to relax wrinkles) or Fillers (to restore volume).
Book Your Natural Glow
To restore your skin’s health with the power of your own biology, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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Sanakin (also known as ACRS – Autologous Cytokine Rich Serum) is an advanced biological therapy that multiplies the anti-inflammatory proteins in your own blood. By incubating your blood for 3 hours, we create a potent serum that acts like “Natural Cortisone” to stop inflammation and regenerate tissue.
It is widely used for Knee Osteoarthritis, Skin Rejuvenation, and Hair Loss in our Nişantaşı, Istanbul clinic. Because it is derived entirely from the patient’s own body, it is naturally well-tolerated and does not carry the typical risks associated with synthetic medications.
Sanakin vs. PRP: What’s the Difference?
● PRP: Acts like a “Construction Worker” (Builds tissue). It is great, but sometimes not enough if there is severe inflammation.
● Sanakin: Acts like a “Firefighter” AND a “Construction Worker” (Stops inflammation + Builds tissue). Because it neutralizes inflammation (using IL-1Ra proteins), it is far superior to PRP for painful joints and inflamed skin conditions (acne, rosacea).
Treatment Areas
We use this technology across three main disciplines. Click to learn more about your specific concern:
1. Pain Management (Knees & Joints) A suitable option for individuals seeking effective pain reduction without the systemic concerns commonly associated with corticosteroid injections. It stops the “biological fire” in the knee and protects cartilage. 
2. Aesthetic Medicine (Skin & Face) Aging and skin problems are often caused by “micro-inflammation.” Sanakin calms chronic redness (Rosacea), improves elasticity, and restores a healthy glow. 
3. Hair Restoration It strengthens hair follicles by reducing scalp micro-inflammation and is
excellent for post-transplant recovery. 
The Process: 3 Hours of Bio-Manufacturing
1. Blood Draw: We take a small amount of blood into special tubes containing medical-grade glass beads.
2. Incubation: Your blood is kept at body temperature (37°C) for 3 hours. The glass beads stimulate your blood cells to produce massive amounts of healing proteins.
3. Application: The golden serum is separated and injected.
Note for Tourists: You can give blood, enjoy shopping or dining in Nişantaşı for 3 hours, and return for the quick injection.
Frequently Asked Questions (FAQ)
● Question: Does it contain drugs?
● Answer: No. The treatment is prepared exclusively using the patient’s own blood
components. It boosts your body’s own anti-inflammatory proteins, making it a safe
alternative to synthetic drugs.
● Question: When will I feel pain relief?
● Answer: For joint pain, patients often report significant relief and improved mobility
within the first week as the inflammation subsides.
● Question: How many sessions?
● Answer: Usually 1 to 3 sessions for joints, and 3 sessions for skin/hair.
● Question: Is it a Stem Cell treatment?
● Answer: No. Regenerative cells are obtained from adipose tissue or bone marrow
sources.
● Sanakin is a protein therapy. However, they work very well together.
● Question: What is the cost?
● Answer: Prices depend on the number of kits used. Treatment in Turkey offers
access to this German technology at a much more affordable rate than in Europe or
the US.
Book Your Natural Therapy
To learn if Sanakin is the right solution for your pain or aesthetic goals, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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Hair Mesotherapy is a medical procedure involving the micro-injection of vitamins, minerals, and peptides directly into the scalp. At our Nişantaşı, Istanbul clinic, we
customize the injection cocktail based on the specific cause of hair loss (genetic, stress, or seasonal) to stop shedding and strengthen hair roots.
What Is Hair Mesotherapy?
Hair follicles are highly active structures requiring constant nutrients. However, due to poor circulation or systemic imbalances, essential vitamins may not effectively reach the scalp. Hair Mesotherapy bridges this gap by delivering bio-stimulants (Biotin, Zinc, Peptides, etc.) directly to the target tissue, ensuring maximum absorption.
Functional Medical Approach (Our Difference)
Hair loss is often a sign of internal imbalance. Before treatment, we evaluate root causes:
● Stress & Adrenal Health (Cortisol): Chronic stress pushes hair follicles into the shedding phase. If needed, we utilize advanced tests like salivary cortisol analysis to assess your biological stress load.
● Iron (Ferritin) Levels: Is there a deficiency?
● Thyroid Function: Is metabolism regulated?
● Nutritional Status: Are there micronutrient gaps? The treatment protocol often runs parallel to correcting these internal factors.
Which Cocktail for Which Condition? (Personalized Protocol)
We do not use a “one-size-fits-all” formula. The ingredients are selected based on your diagnosis:
1. Stress & Seasonal Shedding: Focuses on improving circulation and replacing nutrients lost due to high cortisol.
● Ingredients: B-Complex Vitamins (Biotin), Zinc, Amino Acids, and Vasodilators.
2. Genetic / Male Pattern Hair Loss (Androgenetic): Focuses on counteracting the effects of DHT hormone on roots.
● Ingredients: Growth factors, Copper Peptides, and enzyme blockers.
3. Post-Procedure & Compromised Hair Areas: Supports tissue recovery and helps maintain the vitality of newly implanted or weakened hair follicles.
● Ingredients: Hyaluronic Acid, Organic Silica, and tissue-repairing agents.
The Procedure
1. Application: The scalp is cleaned. The customized solution is injected into the dermis (1-2 mm deep) using very fine sterile needles.
2. Comfort: Discomfort is minimal. Cooling sprays or topical anesthetics can be used if necessary.
3. Protocol: Typically, a course of 6 to 10 sessions is recommended, performed at weekly intervals.
Frequently Asked Questions (FAQ)
1. Is the same medication used for everyone? No. The cause of hair loss varies. We select specific
cocktails rich in peptides, vitamins, or minerals depending on whether your hair loss is genetic,
hormonal, or stress-related.
2. What is the difference between PRP and Mesotherapy?
● PRP: Uses your own blood components (Growth Factors). It repairs tissue.
● Mesotherapy: Uses external vitamins and minerals. It feeds the hair.
● Ideally, combining both yields the best results.
3. Will hair loss return after treatment stops? Mesotherapy strengthens existing hair. However,
since genetic hair loss is chronic, we recommend a single “maintenance session” every 3–4
months after the initial course to keep the results.
4. Does it regrow hair on bald areas? Medically, non-surgical treatments cannot revive dead
follicles on completely bald skin. Mesotherapy aims to thicken and revitalize weak, miniaturized
hairs, improving density.
5. Is it painful? Most patients report only mild prickling. It is generally well-tolerated.
6. Can I dye my hair? We recommend avoiding hair dye and harsh chemicals for at least 2–3 days
after the session to prevent scalp irritation.
7. What is the cost? Pricing depends on the specific ingredients used (e.g., peptide-rich vs.
standard) and the number of sessions. Please contact our clinic for details.

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Rectal Ozone Therapy (Rectal Insufflation) is a medical procedure where ozone gas is administered into the body via the rectum. It provides powerful systemic benefits similar to IV Ozone but without the need for needles or blood withdrawal. The rectal lining is highly absorbent. When ozone is introduced here, it is rapidly absorbed into the bloodstream, offering a painless, safe, and effective alternative for patients who prefer a non-invasive approach.
How Does It Work? (The Liver Connection)
It’s scientifically proven, not just a simple alternative.
1. Rapid Absorption: The gas is absorbed by the intestinal walls within seconds.
2. Direct to Liver: Through the Portal Vein, the ozone goes straight to the liver. This makes it an exceptional therapy for liver detoxification and support.
3. Systemic Boost: From the liver, it enters the general circulation, oxygenating the entire body.
Who Should Choose Rectal Ozone?
● Needle Phobia: Perfect for those who are afraid of needles or blood.
● Difficult Veins: Ideal for patients (e.g., post-chemotherapy) whose veins are fragile or hard to find.
● Gut Health Issues: Excellent for local support in Colitis, IBS, Candida, and parasites.
● Liver Support: For patients needing hepatic detoxification.
The Procedure: Quick & Private
● Time: Takes only 5-10 minutes.
● Comfort: It is typically painless. You may feel a slight sensation of fullness, which passes quickly.
● Equipment: We use ultra-thin, sterile, single-use catheters for maximum hygiene and comfort.
Frequently Asked Questions (FAQ)
● Question: Will I have gas or leakage afterwards?
● Answer: This is a common worry, but unfounded. Ozone gas is absorbed by the
body extremely fast (seconds). There is typically no gas left to “leak” out after the
procedure. You can return to work or social activities immediately without fear of
accidents.
● Question: Is it hygienic?
● Answer: Absolutely. We use a completely closed system with disposable sterile
catheters. Privacy and medical hygiene standards are strictly maintained.
● Question: Is it as effective as IV Ozone (Major)?
● Answer: Answer: Current clinical observations indicate that rectal ozone therapy can
provide a high level of systemic biological support comparable to intravenous ozone
applications. For gut and liver issues, it is often more effective than the IV method.
● Question: Do I need an enema beforehand?
● Answer: No, a full enema is not required. Simply having a bowel movement before
your appointment is sufficient.
● Question: What is the price?
● Answer: Rectal ozone is generally more cost-effective than IV ozone as it requires
fewer medical supplies. Please contact us for a personalized package quote.
Book Your Needle-Free Session
To discuss if Rectal Ozone is the right option for your health, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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Radiesse is an FDA-approved calcium hydroxyapatite (CaHA) biostimulator engineered to restore skin quality, elasticity, and firmness by triggering the body’s own collagen production. It is not a volumizing filler but a regenerative treatment. At our clinic in Nişantaşı, Istanbul, we specialize in “Hyperdilute Radiesse” protocols to tighten loose skin on the face, neck, and body, offering a premium experience for our international patients.
What Is Radiesse?
Radiesse is a powerful injectable biostimulator made of Calcium Hydroxyapatite (CaHA) microspheres. Unlike traditional Hyaluronic Acid fillers that simply add volume, Radiesse works biologically to rejuvenate the skin’s architecture.
Key Benefits:
● Collagen Stimulation: Supports the skin’s natural regeneration process by promoting fibroblast-mediated Type I and Type III collagen production over time.
● Skin Tightening: Improves dermal thickness and smooths crepey texture.
● Non-Volumizing: Ideal for patients who want to avoid the “puffy” or “over-filled” look.
Which Treatment Is Right for You?
To help you decide, here is how Radiesse compares to other popular injectable treatments available in our clinic:
1. Radiesse (CaHA)
● Primary Goal: Skin tightening, structural improvement, and long-term quality.
● Mechanism: Biostimulation (Active collagen production).
● Longevity: 12–18 Months.
● Volume Effect: None / Minimal (when used in Hyperdilute form).
2. Dermal Fillers (Hyaluronic Acid)
● Primary Goal: Restoring lost volume and shaping contours (e.g., Lips, Cheeks).
● Mechanism: Filling hollow spaces physically.
● Longevity: 6–12 Months.
● Volume Effect: High / Immediate volume.
3. Mesotherapy / Skin Boosters
● Primary Goal: Deep hydration and surface glow.
● Mechanism: Moisture retention.
● Longevity: 3–6 Months.
● Volume Effect: None.
Why Does Skin Age? How Does CaHA Help?
As we age, fibroblast activity slows down. This leads to a weakened Extracellular Matrix (ECM),
resulting in sagging and crepey skin. When Radiesse is injected, the CaHA microspheres act as a scaffold. They physically stimulate
fibroblasts to “wake up” and start producing new collagen. Histological studies confirm that this creates a denser, younger-looking dermis.
What Is Hyperdilute Radiesse?
Hyperdilute Technique:
The hyperdilute technique is designed to prioritize skin quality improvement by enhancing tissue diffusion rather than volumization. This transforms it from a thick filler into a spreadable, skin-rejuvenating wash.
● Targeted Tightening: Perfect for larger areas like the neck or décolletage.
● Natural Results: No risk of lumps or unnatural volume changes.
● Versatility: Can be used on the body as well as the face.
Treatment Areas
● Neck & Décolletage: Smooths “Turkey neck” and horizontal chest wrinkles.
● Mid/Lower Face: Tightens skin without changing facial shape.
● Hands: Restores volume to bony hands and hides visible veins.
● Body: Inner arms and abdomen (post-pregnancy laxity).
⚠️ Do We Use Radiesse for Jawline?
No. Transparency is our priority.
In my clinical practice, I do not use Radiesse for volumetric jawline contouring. I strictly use it as a skin
quality agent. If a patient requires jawline definition or chin projection, I prefer Hyaluronic Acid (HA)
fillers for safer, reversible, and more precise structural results.
Plan Your Visit: Nişantaşı & Logistics
For our international patients, we ensure a seamless experience:
● Location: Our clinic is located in Nişantaşı, Istanbul’s most prestigious fashion and lifestyle
district. We are walking distance from luxury hotels like The St. Regis and The Stay.
● Short Stay: Radiesse is a “lunchtime procedure.” You can have the treatment and
immediately enjoy shopping or dining in the neighborhood.
● Flight Safety: You can safely fly the next day. The clinic is approximately 45 minutes from
Istanbul Airport (IST).
Powerful Combinations
Radiesse is effective on its own, but can be combined with other treatments for holistic results:
● Botox: While Radiesse tightens the skin structure, Botox relaxes dynamic wrinkles for a
smoother look.
● Mesotherapy / Skin Boosters: Radiesse builds the collagen scaffold, while skin boosters
provide deep hydration and surface glow.
Our Clinical Approach & Comfort
Patient safety and comfort are our top priorities.
● Pain Management: With a background in Anesthesiology, Dr. Şahin ensures that pain
management is optimized, making the procedure virtually painless.
● Customized Protocols: We avoid “one-size-fits-all” approaches; protocols are strictly
customized based on skin thickness and aging grade.
FAQ (Frequently Asked Questions)
1. Is Radiesse a filler? Technically yes, but in our clinic, we utilize it primarily as a biostimulator to
improve structure rather than add bulk volume.
2. Can Radiesse be dissolved? Unlike Hyaluronic Acid fillers, Radiesse cannot be dissolved
immediately with an enzyme. This is why choosing an expert physician is crucial for safety and
aesthetic success.
3. How many sessions do I need? Treatment Sessions:
Visible skin quality improvement can often be observed after a single session, although treatment
response varies according to individual skin characteristics. For severe laxity, a second session may
be recommended after 2-3 months.
4. When will I see results? You may see an immediate glow, but the real structural improvement
begins at 4 weeks as new collagen forms, peaking around the 3-month mark.
5. Is it painful? No. We mix the product with lidocaine (local anesthetic), and use a gentle cannula
technique to ensure minimal discomfort.
6. Can I fly after the treatment? Yes, it is safe to fly the next day. There are no pressure-related
restrictions for this treatment.
7. How long does the effect last? Results typically last between 12 to 18 months, depending on
your lifestyle and skin type.
8. Are there any side effects? Common side effects include mild swelling or bruising, which usually
resolves within a few days. The Hyperdilute technique minimizes these risks significantly compared to
standard fillers.

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PRP (Platelet Rich Plasma) is a natural regenerative therapy that uses a high concentration of your own platelets to stimulate hair growth, rejuvenate skin, and repair joints.
At our clinic, we do not use standard laboratory tubes. We use Certified Medical Kits that yield a much higher concentration of growth factors compared to generic PRP treatments, ensuring better and faster results.
Why “Medical” PRP Matters ?
Not all PRP is created equal.
● Standard PRP: Often uses cheap test tubes, yielding low platelet counts. Results are weak.
● Medical PRP (Our Standard): Uses specialized kits designed to separate and concentrate platelets effectively. This delivers a potent dose of “repair cells” to the target area.
1. PRP for Hair Loss
● Goal: To stop shedding and thicken existing hair.
● Ideal For: Men and women with thinning hair or post-hair transplant patients.
● Note: For advanced hair loss, we may recommend Sanakin Technology or Micrograft
Therapy for stronger results.
2. PRP for Face (Vampire Facial)
● Goal: To achieve the “Glass Skin” effect, reduce fine lines, and boost collagen.
● Ideal For: Dull, tired skin and fine wrinkles.
● Note: For acne scars or rosacea, Sanakin Skin Therapy is often more effective.
3. PRP for Knees & Joints
● Goal: To lubricate the joint and repair cartilage damage naturally.
● Ideal For: Mild arthritis, sports injuries, and joint pain.
● Note: If you have severe pain and inflammation, Sanakin (Natural Cortisone) is the superior choice.
The Procedure
● Time: Only 30-45 minutes (Blood draw + Preparation + Injection).
● Pain: We use numbing cream for skin/hair and advanced painless techniques for joints.
● Downtime: None. Most patients are able to resume their usual daily activities shortly after the procedure.
Frequently Asked Questions (FAQ)
● Question: How many sessions do I need?
● Answer: A standard protocol is usually 3 sessions, spaced 2-3 weeks apart.
● Question: Is it safe?
● Answer: Answer: The treatment is autologous, meaning it is derived from the
patient’s own cells. This significantly minimizes the risk of immunologic or allergic
reactions.
● Question: Can I combine it with Hair Transplant?
● Answer: Absolutely. PRP increases the survival rate of transplanted grafts and
speeds up healing.
● Question: What is the price?
● Answer: Pricing depends on the quality of the kit used. We strictly use high-quality
medical kits for patient safety and efficacy.
Book Your Regenerative Session
To maximize your body’s healing potential, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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