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Commonly known as “Rejuran Eye,” Rejuran I is a specialized formulation of Polynucleotides (PN) derived from wild salmon DNA. It is specifically designed for the delicate, thin skin around the eyes. Unlike traditional fillers, it does not aim to add artificial volume. Instead, it boosts the tissue’s own capacity to repair itself. Dr. Ömer Fatih Şahin’s Note: “Dark circles are not always caused by a ‘hollow’ that needs filling. Often, the issue is the thinning of the skin, making the underlying blood vessels visible. Rejuran I
solves this root cause naturally by thickening and strengthening the dermis.”
Mechanism of Action: How It Works
When injected, Rejuran I triggers four key biological processes in the eye area:
1. Dermis Thickening: It increases the density of the thin skin under the eyes, reducing the visibility of dark vessels underneath.
2. Collagen Synthesis: It activates fibroblast cells to tighten loose skin around the eyes.
3. Microcirculation Regulation: It revitalizes sluggish blood circulation, helping to reduce dark circles and puffiness.
4. Elasticity Improvement: It smooths out fine lines, often referred to as “crepey skin.”
Comparative Analysis: Rejuran I or Tear Trough Filler?
The most common question from our patients is: “Doctor, should I get filler or Rejuran for my eyes?”
These two treatments serve different needs. Here are the key differences:
● Primary Goal: Fillers aim to fill hollows. Rejuran I aims to repair thin skin, thicken the dermis, and treat dark circles biologically.
● Risk Factor: Fillers carry a risk of water retention (edema) and the Tyndall effect (bluish tint). Rejuran I is a biological healer; it does not cause edema and looks completely natural.
● Volume Effect: Fillers provide instant volume. Rejuran I does not add volume; it improves tissue quality.
● Appearance: Fillers can sometimes create a “puffy” look. Rejuran I maintains your natural eye structure while providing a rested, youthful appearance.
Functional Medicine & Holistic Approach
Dark circles and eye bags are not just aesthetic flaws; sometimes they are a cry for help from the body. When planning treatment at our clinic, we also consider:
● Iron Deficiency: Anemia is a leading cause of dark circles.
● Sleep & Stress: Fatigue and high cortisol impair lymphatic drainage.
● Kidney & Liver Load: Eye bags can sometimes indicate systemic edema.
● Allergies: Histamine release can darken the eye area.
Our aim is not just to inject, but to address the root cause of “tired eyes” for lasting wellness.
Who Is It Suitable For?
It is the ideal treatment for candidates with:
● Thin skin and visible veins under the eyes.
● Dark circles and pigmentation around the eyes.
● Crow’s feet and fine lines (crepey skin).
● A fear of tear trough fillers or those unsuitable for fillers.
● Previous bad experiences with fillers (e.g., persistent edema).
Frequently Asked Questions (FAQ)
Are Rejuran I and Rejuran Healer the same? While they contain the same ingredient (Polynucleotide), their viscosity differs. Rejuran I is more fluid and delicate, specifically produced to spread evenly in the thin skin around the eyes. Healer is denser and used for the rest of the face.
Is the procedure painful? The eye area is sensitive, but thanks to Dr. Ömer Fatih Şahin’s expertise in Anesthesiology, we use special numbing protocols to ensure the highest level of comfort during the procedure.
How many sessions are needed? Depending on the severity of the damage, we generally recommend a course of 3-4 sessions, spaced 2-3 weeks apart.
How long does it last? Since the result is your skin’s own repair, it is long-lasting. However, as the aging process continues, maintenance sessions are recommended every 6-9 months.

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Rejuran Healer is a concentrated form of Polynucleotides (PN) derived from Pacific salmon DNA, which shows high compatibility with human DNA. It is not a filler. When injected into the skin, it acts as a bio-stimulator, repairing damaged tissue from within. Dr. Ömer Fatih Şahin’s Note: “Instead of adding a foreign substance to the skin, Rejuran acts like a project manager, waking up the ‘construction workers’ (fibroblasts) of your skin to start the repair process naturally.”
Mechanism of Action: How It Works
Rejuran Healer triggers four main biological processes:
1. ECM (Extracellular Matrix) Repair: It stabilizes and strengthens the scaffold of the skin.
2. Fibroblast Activation: It stimulates fibroblasts—the fountain of youth cells—to increase Type I and Type III collagen production.
3. Anti-Inflammatory Effect: It suppresses micro-inflammation in the skin, reducing redness and sensitivity.
4. Angiogenesis (Circulation Support): It regulates microcirculation, improving skin oxygenation and glow.
Comparative Analysis: Rejuran Healer or Dermal Fillers?
The most frequent question we hear is: “Doctor, is this a filler? Will it make my face puffy?” No, Rejuran Healer is not a filler. Here are the distinctions:
● Primary Goal: Fillers aim to fill voids and add volume. Rejuran Healer aims to improve skin quality and repair damage.
● Fillers can make areas look fuller. Rejuran Healer does not plump the face; it works on improving skin quality instead.
● Target Tissue: Fillers are often placed deep (on bone or fat pads). Rejuran is injected into the Dermis (the skin layer).
● Result Timeline: Fillers show instant results. Rejuran results appear gradually over 3-4 weeks as biological repair occurs.
● Look: Fillers provide contour. Rejuran provides tighter, smoother, and more radiant skin texture.
Functional Medicine & Holistic Approach
At our clinic, we don’t view Rejuran Healer merely as an injection. Skin quality is directly linked to gut health, sleep patterns, and stress levels.
We evaluate factors such as:
● Stress Management: High cortisol accelerates collagen breakdown.
● Nutrition: Sugar and processed foods age the skin via “Glycation.”
● Micronutrient Support: We ensure optimal vitamin/mineral balance to boost the effects of Rejuran.
Our goal is not temporary shine, but a biologically healthier and more resilient tissue environment.
Who Is It Suitable For? (Indications)
This protocol is ideal for individuals with:
● Skin that has lost elasticity and is prone to sagging.
● Enlarged pores and sebum (oil) imbalance.
● Acne scars (atrophic scars) and uneven skin texture.
● Dull, dehydrated, and “tired-looking” skin.
● Fine wrinkles starting to appear (especially on the neck and cheeks).
Frequently Asked Questions (FAQ)
Will Rejuran Healer change my face shape? No. Since it is not a filler, it does not alter your facial features or create puffiness. It simply improves the texture and youthfulness of your skin.
Is the procedure painful? The treatment involves micro-injections. Thanks to Dr. Ömer Fatih Şahin’s Anesthesiology background, pain management and patient comfort are maximized through special pre-procedure protocols.
Can it be done in summer? Yes. Rejuran does not cause photosensitivity (sun sensitivity). On the contrary, because it strengthens the skin barrier, it is a safe and excellent choice before or after summer to repair sun damage.

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Sanakin represents a breakthrough in the non-surgical treatment of Knee Osteoarthritis and chronic joint pain. By processing your own blood to multiply anti-inflammatory proteins, we create a powerful serum that stops pain and protects cartilage without chemicals. For patients who want to avoid knee replacement surgery or are wary of the side effects of steroid injections, Sanakin offers a potent, biological alternative. At our clinic, Specialist Dr. Ömer Fatih Şahin applies this German technology with the precision of a pain management expert.
Why Sanakin instead of PRP for Knees?
Standard PRP is great for repair, but it struggles if there is severe inflammation in the joint.
● The Problem: Inflammation (swelling/heat) eats away at your cartilage and causes pain.
● The Solution (Sanakin): It contains high concentrations of IL-1Ra, a protein that specifically blocks the inflammation receptors. It effectively “puts out the fire” inside your knee, creating a safe environment for healing.
Who is the Ideal Candidate?
● Knee Osteoarthritis: Patients experiencing stiffness, pain while climbing stairs, or “loss of
fluid” (Stages 1-3).
● Meniscus Tears: To manage pain and promote healing in degenerative tears.
● Athletes: For rapid recovery from runner’s knee or ligament strains.
● Anti-Cortisone Patients: Those looking for a 100% natural, drug-free pain relief method.
The Process: How it Works
1. Blood Draw: We take blood into special Sanakin tubes.
2. 3-Hour Incubation: Your blood is kept at body temperature. During this time, your cells produce the healing serum. (Perfect time for a lunch or shopping break in Nişantaşı).
3. Injection: The serum is injected into the knee joint painlessly.
Frequently Asked Questions (FAQ)
● Question: Is it better than Cortisone shots?
● Answer: In terms of safety and long-term health, Yes. Cortisone stops pain quickly
but can damage cartilage over time. Sanakin stops pain naturally and protects the
cartilage from further degeneration. It has no side effects.
● Question: Can it prevent surgery?
● Answer: In mild to moderate cases of arthritis, it can significantly delay or even
eliminate the need for knee replacement surgery by preserving joint health.
● Question: Does the injection hurt?
● Answer: Dr. Şahin is an Anesthesiologist. He uses advanced techniques to ensure
the knee injection is virtually painless. There is no need for post-treatment
observation, and patients can depart immediately.

● Question: How many sessions do I need?
● Answer: Typically, a series of 1 to 3 injections is recommended depending on the
severity of your pain.
● Question: Can I combine it with Hyaluronic Acid (Gel)? Answer: Yes, this is a powerful
combination, but timing is key. We use a staged protocol: First, we use Sanakin to stop the
active inflammation (the fire) in the joint. Then, about 3 weeks later, we inject Hyaluronic Acid
to lubricate the joint. This ensures the gel works better in a healthy, inflammation-free
environment.
Book Your Knee Relief
To find out if Sanakin is the right biological treatment for your knees, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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Occipital Nerve Block is a medical procedure involving the injection of local anesthetics around the nerves at the back of the head. It is utilized to manage pain transmission in patients diagnosed with chronic migraine, occipital neuralgia, and tension-type headaches. This procedure is performed by Dr. Ömer Fatih Şahin in Nişantaşı, Istanbul as part of a comprehensive pain management plan.
What Is an Occipital Nerve Block?
Headaches often originate from the irritation or compression of the Greater and Lesser Occipital Nerves located at the base of the skull. The Occipital Nerve Block serves to interrupt the transmission of pain signals from these nerves to the brain. Medical Objective: To desensitize the central nervous system, reduce the frequency and
intensity of headache attacks, and provide relief for patients resistant to standard medication.
Medical Indications (Who Is It For?)
This procedure is planned after a thorough neurological and physical examination. It may be indicated for:
● Chronic Migraine: For patients seeking to manage pain with fewer oral medications.
● Occipital Neuralgia: Characterized by piercing, throbbing, or electric-shock-like pain in the upper neck and back of the head.
● Cervicogenic Headache: Headaches originating from cervical spine (neck) issues.
● Cluster Headaches: To provide temporary relief during active cluster periods.
Procedure Protocol
The procedure is performed in a clinical setting under sterile conditions.
1. Anatomical Mapping: The physician identifies the specific location of the Greater Occipital Nerve (GON) through palpation.
2. Injection: Using a fine-gauge needle, the medication (local anesthetic, sometimes combined with a corticosteroid) is injected into the tissue surrounding the nerve. The nerve itself is not penetrated.
3. Process: The procedure takes approximately 5–10 minutes. Afterwards, the patient is monitored for 15–20 minutes to ensure stable vital signs before discharge.
Holistic (Functional) Assessment
While the nerve block addresses the symptom (pain), our clinic also investigates potential underlying triggers through a Functional Medicine perspective:
● Posture analysis and muscle tension.
● Sleep disorders (Sleep Apnea).
● Micronutrient deficiencies (Magnesium, B12).
● Chronic inflammation markers.
Frequently Asked Questions (Informational)
1. Is the procedure painful? There is minimal discomfort associated with the needle insertion and a
slight pressure sensation during the injection. The local anesthetic provides rapid numbness to the
area.
2. How long does the effect last? Pain relief from the anesthetic is immediate. The therapeutic
benefit (reduction in headache frequency) varies by patient, potentially lasting weeks or months.
Chronic conditions may require repeat sessions.
3. Are there risks? It is considered a safe procedure when performed by a qualified specialist. Minor
side effects may include temporary tenderness at the injection site or mild dizziness. Serious
complications are rare.
4. Is it a permanent cure? In medicine, terms like “permanent cure” are not used for chronic
conditions like migraine. This procedure is an effective management tool designed to improve quality
of life and reduce pain scores.
5. Can I drive afterwards?
Normal daily routines can usually be resumed shortly after the procedure. However, driving
immediately after the procedure is not recommended if it is your first time, due to potential mild
dizziness.
6. What is the cost? Pricing depends on the specific medication protocol and number of sessions
required. Per regulations, medical fees cannot be published online. Please contact our clinic for
consultation.

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What Is Neural Therapy? (More Than Pain Relief) Originating in Germany in the 1920s and widely used across Europe, this technique bridges modern neurology with Eastern wisdom, often targeting specific acupuncture points alongside anatomical nerves. It works by repairing “short circuits” in your body’s electrical wiring system caused by old scars, surgeries, or trauma. Neural Therapy uses Procaine or Lidocaine, not to numb pain temporarily, but to restore the electrical potential of the nerve cells. It’s essentially hitting the “Reset Button” on your nervous system.
The “Interference Field” Concept This is the core philosophy of Neural Therapy. An Interference Field is damaged tissue (like a scar, a burn mark, or a bad tooth) that sends constant stress signals to the Autonomic Nervous System, confusing the brain. Example: A patient with chronic knee pain might actually be suffering from an interference field in their tonsils due to a childhood infection. Treating the tonsils can surprisingly cure the knee pain. This holistic connection is what makes Neural Therapy unique compared to conventional medicine.
Conditions Treated It is highly effective for conditions where the body’s regulation is blocked:
● Chronic Pain: Back pain, Neck pain, Migraines, Tension headaches.
● Autoimmune & Rheumatic: Fibromyalgia, Hashimoto’s (supportive), Rheumatoid Arthritis.
● Women’s Health: Menstrual cramps (Dysmenorrhea), Menopause symptoms, Infertility (supportive).
● Stress & Mood: Chronic Fatigue Syndrome, Anxiety, Sleep disorders, Restless Leg Syndrome.
The Procedure in Istanbul
1. Finding the Cause: Dr. Ömer Fatih Şahin takes a detailed life history (Timeline) to identify your potential interference fields (scars, surgeries, vaccinations, dental history).
2. The Injection: Using very fine needles (hair-thin), micro-injections are made into scars, nerves (ganglions), or acupuncture points.
3. The Protocol: Sessions are typically weekly. A full course of 3 to 10 sessions is common, depending on how chronic the condition is.
Frequently Asked Questions (FAQ)
Question: Does it contain Cortisone/Steroids? Answer: No. Neural Therapy solutions are strictly
free from steroids/cortisone. They contain only local anesthetics (Procaine/Lidocaine), and sometimes
homeopathic remedies or saline. It is a biological regulation therapy.
Question: Is it painful? Answer: Not really. The needles are extremely thin (like insulin needles).
You typically feel a small pinch, often described by patients as a “mosquito bite.”
Question: Is it safe for pregnancy? Answer: Neural Therapy is considered close to a “drug-free”
treatment (the anesthetic is eliminated from the body within 20 minutes). This treatment is
contraindicated during pregnancy. It can be safely administered to breastfeeding mothers. The final
decision always depends on the physician’s examination.
Question: How fast does it work? Answer: Sometimes, the relief is instant (known as the “Flash
Phenomenon”). For chronic, long-standing conditions, improvement builds up progressively over
several sessions as the nervous system stabilizes.
Question: Is it like Acupuncture? Answer: They share similarities in being holistic, but Neural
Therapy uses injections to fix electrical disturbances in specific anatomical structures, whereas
acupuncture works on energy meridians.
Question: What is the cost in Istanbul? Answer: Prices depend on the complexity of the session.
Treatment in Turkey offers high-standard medical care at a fraction of the cost in the UK, EU, or USA.

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You feel constantly tired. You experience bloating, brain fog, stubborn weight gain, hair loss, or chronic pain. You visit doctors, run tests — and hear the same sentence:
Everything looks normal. But you don’t feel normal.
This is exactly where Functional Medicine begins.
While conventional medicine often focuses on suppressing symptoms, Functional Medicine investigates why those symptoms developed in the first place.
At our clinic, Specialist Dr. Ömer Fatih Şahin approaches the body as an interconnected biological system — not isolated organs.
Functional Medicine vs. Conventional Medicine
Symptoms vs. Root Cause
● Conventional medicine: You have pain → painkiller.
● Functional medicine: Why is inflammation present? What triggered the imbalance?
Organs vs. Systems
● Gut dysfunction can affect thyroid function.
● Hormonal imbalance can impact mental health.
● Chronic stress can disrupt immunity and digestion.
Standard Protocol vs. Personalized Roadmap
There is no one-size-fits-all treatment.
Your protocol is built around your biochemistry, lifestyle, genetics, and metabolic needs.
Conditions We Commonly Treat
Autoimmune Diseases
● Hashimoto’s Thyroiditis
● Rheumatoid Arthritis
● Psoriasis & autoimmune skin conditions
Gut & Digestive Disorders
● IBS (Irritable Bowel Syndrome)
● SIBO (Small Intestinal Bacterial Overgrowth)
● Leaky Gut Syndrome
● Chronic bloating, gas, food sensitivities
Metabolic & Hormonal Imbalances
● Insulin resistance
● PCOS
● Chronic fatigue syndrome & fibromyalgia
● Adrenal dysfunction (burnout)
Our Functional Medicine Process
Step 1 – Comprehensive Medical History
A 60–90 minute deep-dive consultation covering:
● Nutrition and eating patterns
● Sleep quality
● Stress exposure
● Medical and medication history
● Supplement use and lifestyle factors
Step 2 – Advanced Functional Testing
Beyond routine blood tests, we evaluate system-level imbalances:
● SIBO breath testing
● Comprehensive thyroid panels
● Advanced cardiometabolic risk markers
● Hormone and stress-response panels
● Detoxification and metabolic capacity assessment
Step 3 – Personalized “Matrix” Treatment Plan
Your protocol is structured around five essential pillars:
1- Therapeutic Nutrition (Foundation of Healing)
● Elimination Diet
● Autoimmune Protocol (AIP Diet)
● SIBO-specific nutrition strategies
Goal:
Reduce inflammation, repair the gut lining, and regulate immune responses.
2- Oral Supplementation (Core of Sustainable Healing)
This is where long-term recovery happens.
● Targeted vitamin & mineral repletion
● Gut-repair and microbiome support
● Mitochondrial, hormonal, and nervous system support
● Adaptogenic herbs when appropriate
– IV therapies accelerate recovery, but oral supplementation is the backbone of functional
healing.
3- Medical Support Therapies
● Ozone Therapy
● IV Therapies (Glutathione, NAD+, tailored micronutrients)
4- Nervous System & Stress Regulation
● Breathing techniques
● Vagus nerve activation
● Stress resilience strategies
5- Sleep & Movement Optimization
● Circadian rhythm regulation
● Personalized exercise planning
● Avoidance of overtraining in high-stress individuals
Frequently Asked Questions
Do I need to stop my medications?
No. Functional Medicine works alongside conventional care. Medications are reviewed and adjusted
only if clinically appropriate.
Is this just a diet program?
No. Nutrition is essential, but true healing also requires addressing sleep, stress, supplementation, and lifestyle factors.
How long does recovery take?
Most patients notice improvement within 2–4 weeks. Cellular and metabolic restoration typically takes
3–6 months.
Rebuild Your Health from the Inside Out
If you are tired of suppressing symptoms and want to address the true biological causes of your condition, Functional Medicine may be the missing link.
Schedule a consultation with Specialist Dr. Ömer Fatih Şahin to begin a personalized, science-based healing journey.

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Acupuncture is a scientific treatment recognized by the WHO that stimulates the central nervous system by inserting fine needles into specific neuroanatomical points. It triggers the body’s own painkillers (endorphins) and healing mechanisms. At our Nişantaşı clinic, we apply both Body Acupuncture and Ear Acupuncture (Auriculotherapy) for pain relief, stress management, and total body balance.
What is Acupuncture? (Not Just Energy, It’s Science) With a history spanning thousands of years, Acupuncture is today an effective treatment method accepted by the World Health Organization (WHO) and integrated with modern medicine.
How Does It Work? Single-use micro-needles inserted into the skin send specific signals to the brain.
As a result of these signals, the body releases:
● Natural Painkillers: Endorphins and Enkephalins.
● Happiness Hormones: Regulates Serotonin and Dopamine levels (Stress Management).
● Increased Circulation: Accelerates tissue healing by increasing regional blood flow. In short, we can call Acupuncture a key that opens the body’s own pharmacy.
Methods We Apply
1. Body Acupuncture It is applied to points on meridians (energy channels) and nerve junctions on the body. It is preferred for musculoskeletal pain, systemic diseases, and general body balance.
2. Ear Acupuncture (Auriculotherapy) The ear is a microsystem that carries the map of the entire body (think of it like a fetus in the womb). Reflex points on the ear have powerful effects, especially for appetite control/weight loss, addiction treatment, and stress management.
What Conditions Does It Treat? Acupuncture is used alone or as a support to other treatments for:
● Stress & Balance: Chronic stress, anxiety, sleep disorders, and Burnout Syndrome.
● Pain Management: Migraine, Fibromyalgia, Back, Neck, and Lower back pain.
● Weight Control: To balance the appetite mechanism and regulate metabolism.
● Women’s Health: Menstrual irregularities, Stress regulation before IVF (In Vitro Fertilization).
● Digestion: Constipation, Bloating, Gastritis.
The Treatment Process
1. Analysis: Dr. Ömer Fatih Şahin determines the specific acupuncture points to be used through a detailed interview and clinical examination.
2. Application: While the patient is sitting or lying down, sterile, disposable needles (as thin as a hair strand) are placed at specific points.
3. The “Zen” Period: The needles remain in the body for about 20-30 minutes. During this time, the patient experiences deep relaxation (sedation) and peace. Most patients feel a sense of calm reset in our quiet acupuncture room.
4. Ear Seeds/Bands: For Auriculotherapy, in addition to needles, we may apply small acupuncture bands or seeds to the ear. These can remain on your ear for a few days to a week to continue the therapy at home.
Frequently Asked Questions (FAQ)
● Question: I have no pain, can I get it just for relaxation and balance?
● Answer: Absolutely. In modern life, the most common reason for acupuncture is stress management and body regulation. One of the most powerful effects of
acupuncture is to calm the Sympathetic (Stress) System and restore the Sympathetic-Parasympathetic balance. For those experiencing chronic fatigue, burnout, or high stress, regular sessions are recommended to return the body to factory settings and provide deep mental/physical relaxation.
● Question: Do the needles hurt?
● Answer: No. Acupuncture needles are much thinner and more flexible than injection needles. At the moment of insertion, you may feel a minimal sensation like a mosquito bite. Once the needles are in, a feeling of deep peace and heaviness begins; many patients actually fall asleep during the session.
● Question: Does the program support weight management ?
● Answer: It does not burn fat on its own, but it facilitates the process. It stimulates the satiety center in the brain to balance appetite, reduces stomach cravings, and
most importantly, prevents stress-induced eating attacks (emotional hunger).
● Question: How many session will I need ?
● Answer:
● For Body Relaxation and Balance: A 6-week program consisting of weekly sessions is sufficient for a spiritual detox
● For Pain: 4-8 sessions are recommended depending on the intensity of the pain.
● For Weight Control: Protocols of 10-12 sessions are recommended.
● Question: Are there side effects?
● Answer: Since it is a drug-free method, there are no chemical side effects. It is one of the most natural treatment methods as it uses the body’s own biochemistry. Rarely,
tiny bruises may occur at some needle sites.
● Question: How does this differ from Neural Therapy?
● Answer: In Neural Therapy, diluted lidocaine or procaine is often injected into acupuncture points. In Traditional Acupuncture, we use only special needles without medication; energy meridians are stimulated and regulated solely by the needles.
● Question: What is the price?
● Answer: Pricing is based on session packages. Due to legal regulations, we cannot publish prices on our website. Please contact our clinic for detailed information

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