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SVF Skin Rejuvenation is a transformative procedure where we replenish your skin’s depleted cellular reserves using young, dynamic stem cells from your own fat tissue. This is not a filler; it is true biological repair. As we age, our skin becomes thin, dry, and crepey because we run out of collagen-producing cells. Specialist Dr. Ömer Fatih Şahin uses SVF to transfer millions of new “worker cells” into your skin, effectively turning back the biological clock.
Why SVF for Skin? (True Anti-Aging)
Botox freezes muscles. Fillers fill holes. But neither improves skin quality.
● The SVF Difference: The stem cells transform into fibroblasts, producing your own Collagen and Elastin.
● The Look: It creates a “Glow,” thickens thin skin, and restores elasticity. You look like a younger version of yourself, not “done.”
Target Areas
1. Full Face: For overall tightening and glow.
2. Under Eyes: To treat dark circles and hollows naturally.
3. Neck & Décolletage: Excellent for treating the difficult “turkey neck” texture.
4. Hand Rejuvenation: Hands often reveal age first. SVF restores volume and hides veins/tendons.
Frequently Asked Questions (FAQ)
● Question: Will my face look fat or puffy?
● Answer: No. We filter out the fat cells. We only inject the regenerative cells (SVF).
There is no risk of a “pillow face.”
● Question: When will I see results?
● Answer: This is a biological process. You will see a “glow” in Month 1. The real
tightening and rejuvenation peak around Month 3, as new collagen is built.
● Question: Is the fat harvesting painful?
● Answer: No. It is done under local anesthesia. We take a very small amount (like a
coffee cup). Post-procedure discomfort is minimal and does not affect your daily life.
Invest in Your Skin
For a natural, biological, and long-lasting rejuvenation, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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SVF (Stromal Vascular Fraction) is a cutting-edge regenerative procedure where millions of potent stem cells are harvested from your own fat tissue, processed immediately, and re-injected to heal and rejuvenate your body. Did you know? Your fat tissue contains 500 to 1,000 times more Mesenchymal Stem Cells (MSCs)
than bone marrow. SVF Therapy taps into this rich biological reserve. At our clinic, Specialist Dr. Ömer Fatih Şahin performs this procedure using a “Closed-Circuit Sterile System,” ensuring the highest safety standards for our international patients.
Why is it the Strongest Option? (The Biological Soup)
SVF is not just one type of cell. It is a powerful “Regeneration Cocktail” containing:
● Stem Cells (ADSCs): The master builders that repair damaged tissue.
● Growth Factors: Signaling proteins that kickstart the healing process.
● Pericytes: Cells that improve blood supply and oxygenation.
● T-Reg Cells: Potent anti-inflammatory agents that calm aging or damaged skin.
Treatment Areas
Since this is your body’s most powerful repair material, we use it for two major aesthetic concerns.
1. Hair Restoration & Transplant Support The ultimate rescue for thinning hair and the perfect booster for Hair Transplant success. 
2. Full-Face Rejuvenation & Anti-Aging Reverse biological aging on the face, neck, and hands without the “puffy” look of fillers. 
The Process: Not Surgery, Just a “Mini-Harvest”
International patients often worry about “liposuction.” Rest assured, this is not a major surgery.
1. Mini-Harvest (20 Mins): Under local anesthesia, we gently extract only a small amount (60-80cc – a cup’s worth) of fat from the abdomen. It is painless and requires no stitches.
2. Isolation (60 Mins): The fat is processed in a sterile system. We discard the oil and fat cells, keeping only the pure, live stem cells.
3. Injection (15 Mins): These live cells are injected into the target area (scalp or face).
Frequently Asked Questions (FAQ)
● Question: Is it the same as Fat Grafting (Fat Transfer)?
● Answer: No. Fat grafting adds Volume (Filler effect). SVF adds Repair (Medicine
effect). In SVF, we remove the bulky fat cells, so you don’t get a swollen face. You get
tighter, younger skin.
● Question: Is one session enough?
● Answer: Yes. SVF is a long term investment for your tissue. It is typically a
single-session protocol. The results evolve over months and last for years
depending on your biological aging.
● Question: Will I have scars?
● Answer: No. The fat is harvested through a tiny 2mm puncture which heals without a
visible scar. No stitches are needed.
● Question: What is the cost?
● Answer: Treatment in Turkey offers access to this premium biotechnology at a
significantly more affordable rate than in the US, UK, or EU, without compromising on
quality or safety.
The Future of Medicine is Here
To regenerate your body with your own cells, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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Sanakin is a revolutionary biological treatment that uses your own blood to create a serum rich in anti-inflammatory proteins. It is designed to calm sensitive skin, treat Rosacea, and reverse the signs of aging caused by chronic inflammation. In modern dermatology, we know that aging is largely driven by silent inflammation (Inflammaging). Unlike fillers that just hide the problem, Sanakin stops this inflammation at the cellular level, restoring a healthy, youthful glow.
Why Sanakin over a Vampire Facial (PRP)?
Standard PRP is good, but Sanakin is Smart.
● The Difference: By incubating your blood for 3 hours, Sanakin multiplies the production of Anti-Inflammatory Cytokines.
● The Benefit: While PRP stimulates stimulation, Sanakin provides “Calm Regeneration.” This makes it far superior for patients with sensitive skin, redness, or active acne, where PRP might be too aggressive.
What Does It Treat?
● Rosacea & Chronic Redness: It is one of the few treatments that can calm the “fire” of Rosacea without the heat of lasers.
● Anti-Aging: Improves skin elasticity, reduces fine lines, and tightens pores.
● Acne & Scars: Helps dry out active inflammation and speeds up the healing of acne scars.
● Dark Circles: Improves circulation around the delicate eye area.
The Process: Quality Takes Time
1. Blood Draw: We collect your blood in specialized tubes.
2. 3-Hour Bio-Manufacturing: Your blood is placed in an incubator. This is the magic step where your cells produce the healing serum. (A perfect break to enjoy Istanbul/Nişantaşı).
3. Application: The golden serum is injected into the face, neck, or décolletage using micro-needles.
Frequently Asked Questions (FAQ)
● Question: Is it a filler?
● Answer: No. It does not change your facial shape or freeze your muscles like Botox.
It improves the quality of your skin naturally.
● Question: Is it safe for sensitive skin?
● Answer: Yes, it is the safest option. Since it is 100% autologous (your own blood)
and focuses on reducing inflammation, it is perfect for skin that reacts badly to
chemical peels or lasers.
● Question: How many sessions?
● Answer: We typically recommend a protocol of 3 sessions, spaced 2-3 weeks apart.
● Question: Can I combine it with other treatments?
● Answer: Yes. For total rejuvenation, we often combine Sanakin (to improve skin
quality) with Botox (to relax wrinkles) or Fillers (to restore volume).
Book Your Natural Glow
To restore your skin’s health with the power of your own biology, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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Sanakin (also known as ACRS – Autologous Cytokine Rich Serum) is an advanced biological therapy that multiplies the anti-inflammatory proteins in your own blood. By incubating your blood for 3 hours, we create a potent serum that acts like “Natural Cortisone” to stop inflammation and regenerate tissue.
It is widely used for Knee Osteoarthritis, Skin Rejuvenation, and Hair Loss in our Nişantaşı, Istanbul clinic. Because it is derived entirely from the patient’s own body, it is naturally well-tolerated and does not carry the typical risks associated with synthetic medications.
Sanakin vs. PRP: What’s the Difference?
● PRP: Acts like a “Construction Worker” (Builds tissue). It is great, but sometimes not enough if there is severe inflammation.
● Sanakin: Acts like a “Firefighter” AND a “Construction Worker” (Stops inflammation + Builds tissue). Because it neutralizes inflammation (using IL-1Ra proteins), it is far superior to PRP for painful joints and inflamed skin conditions (acne, rosacea).
Treatment Areas
We use this technology across three main disciplines. Click to learn more about your specific concern:
1. Pain Management (Knees & Joints) A suitable option for individuals seeking effective pain reduction without the systemic concerns commonly associated with corticosteroid injections. It stops the “biological fire” in the knee and protects cartilage. 
2. Aesthetic Medicine (Skin & Face) Aging and skin problems are often caused by “micro-inflammation.” Sanakin calms chronic redness (Rosacea), improves elasticity, and restores a healthy glow. 
3. Hair Restoration It strengthens hair follicles by reducing scalp micro-inflammation and is
excellent for post-transplant recovery. 
The Process: 3 Hours of Bio-Manufacturing
1. Blood Draw: We take a small amount of blood into special tubes containing medical-grade glass beads.
2. Incubation: Your blood is kept at body temperature (37°C) for 3 hours. The glass beads stimulate your blood cells to produce massive amounts of healing proteins.
3. Application: The golden serum is separated and injected.
Note for Tourists: You can give blood, enjoy shopping or dining in Nişantaşı for 3 hours, and return for the quick injection.
Frequently Asked Questions (FAQ)
● Question: Does it contain drugs?
● Answer: No. The treatment is prepared exclusively using the patient’s own blood
components. It boosts your body’s own anti-inflammatory proteins, making it a safe
alternative to synthetic drugs.
● Question: When will I feel pain relief?
● Answer: For joint pain, patients often report significant relief and improved mobility
within the first week as the inflammation subsides.
● Question: How many sessions?
● Answer: Usually 1 to 3 sessions for joints, and 3 sessions for skin/hair.
● Question: Is it a Stem Cell treatment?
● Answer: No. Regenerative cells are obtained from adipose tissue or bone marrow
sources.
● Sanakin is a protein therapy. However, they work very well together.
● Question: What is the cost?
● Answer: Prices depend on the number of kits used. Treatment in Turkey offers
access to this German technology at a much more affordable rate than in Europe or
the US.
Book Your Natural Therapy
To learn if Sanakin is the right solution for your pain or aesthetic goals, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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PRP (Platelet Rich Plasma) is a natural regenerative therapy that uses a high concentration of your own platelets to stimulate hair growth, rejuvenate skin, and repair joints.
At our clinic, we do not use standard laboratory tubes. We use Certified Medical Kits that yield a much higher concentration of growth factors compared to generic PRP treatments, ensuring better and faster results.
Why “Medical” PRP Matters ?
Not all PRP is created equal.
● Standard PRP: Often uses cheap test tubes, yielding low platelet counts. Results are weak.
● Medical PRP (Our Standard): Uses specialized kits designed to separate and concentrate platelets effectively. This delivers a potent dose of “repair cells” to the target area.
1. PRP for Hair Loss
● Goal: To stop shedding and thicken existing hair.
● Ideal For: Men and women with thinning hair or post-hair transplant patients.
● Note: For advanced hair loss, we may recommend Sanakin Technology or Micrograft
Therapy for stronger results.
2. PRP for Face (Vampire Facial)
● Goal: To achieve the “Glass Skin” effect, reduce fine lines, and boost collagen.
● Ideal For: Dull, tired skin and fine wrinkles.
● Note: For acne scars or rosacea, Sanakin Skin Therapy is often more effective.
3. PRP for Knees & Joints
● Goal: To lubricate the joint and repair cartilage damage naturally.
● Ideal For: Mild arthritis, sports injuries, and joint pain.
● Note: If you have severe pain and inflammation, Sanakin (Natural Cortisone) is the superior choice.
The Procedure
● Time: Only 30-45 minutes (Blood draw + Preparation + Injection).
● Pain: We use numbing cream for skin/hair and advanced painless techniques for joints.
● Downtime: None. Most patients are able to resume their usual daily activities shortly after the procedure.
Frequently Asked Questions (FAQ)
● Question: How many sessions do I need?
● Answer: A standard protocol is usually 3 sessions, spaced 2-3 weeks apart.
● Question: Is it safe?
● Answer: Answer: The treatment is autologous, meaning it is derived from the
patient’s own cells. This significantly minimizes the risk of immunologic or allergic
reactions.
● Question: Can I combine it with Hair Transplant?
● Answer: Absolutely. PRP increases the survival rate of transplanted grafts and
speeds up healing.
● Question: What is the price?
● Answer: Pricing depends on the quality of the kit used. We strictly use high-quality
medical kits for patient safety and efficacy.
Book Your Regenerative Session
To maximize your body’s healing potential, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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Autologous Micrograft Skin Therapy is a regenerative anti-aging treatment that harvests young, healthy fibroblast cells from behind your ear and transplants them into your face, neck, or décolletage. Unlike synthetic fillers that artificially volumize the face, this treatment focuses on Bio-Restructuring. It uses your own tissue to repair deep acne scars, smooth out fine lines, and restore the elasticity of your youth. Performed by Specialist Dr. Ömer Fatih Şahin, it is a one-session protocol with
long-lasting results.
Why Behind the Ear?
The donor area provides cells with higher biological activity compared to facial skin. These cells are carefully introduced into areas showing signs of aging to support natural skin regeneration.
● The Process: We act as biological gardeners. We take these “young & healthy” cells and plant them into the “aged & damaged” areas of your face.
● The Result: The transplanted cells start producing new Collagen Type-3 (Baby Collagen) and Elastin, naturally tightening the skin.
Perfect for Acne Scars & Aging
This technology fills the gap where lasers often fail:
1. Acne Scars: For deep, pitted scars (atrophic), lasers resurface the top, but Micrografts build the tissue from underneath, pushing the scar up and smoothing the skin.
2. Crepey Skin: Thickens thinning skin on the neck and hands.
3. Natural Anti-Aging: For patients who say “I don’t want to look fake or puffy.”
Frequently Asked Questions (FAQ)
● Question: Can I do this treatment in summer?
● Answer: Yes, absolutely. Unlike chemical peels or strong lasers that make your skin
sensitive to the sun, Autologous Micrograft therapy works beneath the surface. It
does not peel the top layer of your skin, so it is safe to perform even in sunny months
with standard sun protection.
● Question: Is it a Dermal Filler?
● Answer: No. Fillers are gels that add volume immediately. Micrograft is a cellular
therapy that builds your own tissue over time. It doesn’t change your face shape; it
changes your skin quality.
● Question: How long does it last?
● Answer: Since it regenerates your own tissue, the results are long-lasting. The aging
process continues naturally, but from a “rejuvenated” baseline. A maintenance
session can be done after 1-2 years.
● Question: Can I combine it with lasers?
● Answer: Yes. Combining Micrografts (to build tissue from inside) with Lasers (to
polish the surface) is the ultimate protocol for acne scars and severe aging.
Book Your Biological Facial
To regenerate your skin with the power of your own cells, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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Autologous Micrograft Therapy is a cutting-edge regenerative protocol that utilizes “progenitor cells” harvested from your own tissue (behind the ear) to revitalize hair follicles and skin. It is a powerful, single-session alternative to traditional stem cell treatments. Performed in our Nişantaşı, Istanbul clinic using approved mechanical separation kits, this procedure harnesses the healing power of your own body without chemicals or enzymes. Unlike lab-cultured stem cells that take weeks, this is an immediate “bedside” procedure performed by Specialist Dr. Ömer Fatih Şahin.
How Does It Work? (Seed & Soil Concept)
To understand the difference from PRP:
● PRP provides the “water and fertilizer” (Growth Factors).
● Micrograft provides the “seeds and fertile soil” (Progenitor cells + Extracellular Matrix). The device mechanically separates the tissue into 50-micron particles, preserving the viability of the cells. When injected, these live cells initiate a powerful repair process.
Treatment Areas
This technology is customized based on the tissue we harvest. Click to learn more about your specific concern:
1. Hair Restoration (Androgenetic Alopecia) We harvest from the hairy scalp to get follicle progenitor cells.
● Benefit: Stops hair loss, thickens miniaturized hair, and boosts transplant results. 
2. Skin Rejuvenation & Acne Scars: For this treatment, cell samples are collected from hair-free skin areas to ensure a high concentration of regenerative fibroblast cells.
● Benefit: Increases collagen density, treats acne scars, and improves elasticity. 
The Procedure: The Perfect “Lunchtime” Treatment
1. Harvesting: Under local anesthesia, Dr. Şahin takes 3-4 tiny skin punches (2.5mm) from behind your ear. It is painless and leaves no visible scars.
2. Processing: The tissue is mechanically separated in a sterile device (5 minutes).
3. Injection: The cellular solution is injected into the target area. Total time: 45 minutes. Zero downtime.
Frequently Asked Questions (FAQ)
● Question: Is one session really enough?
● Answer: Yes. For the vast majority of patients, a single session is sufficient. The
biological results are long-lasting. Maintenance can be considered after 12–18
months if needed.
● Question: Is it a Stem Cell treatment?
● Answer: Technically, it is a “Progenitor Cell” therapy. It is safer and faster than
expanded stem cell treatments because it doesn’t involve growing cells in a lab. It
uses your tissue’s natural regenerative potential immediately.
● Question: Can I fly after the treatment?
● Answer: Yes. There is absolutely no downtime. You can return to your social life,
travel, or shopping immediately after the procedure.
● Question: What is the cost?
● Answer: Treatment in Turkey offers access to this advanced technology at a
significantly more affordable rate than in the UK, EU, or USA, while maintaining the
highest medical standards.
Book Your Single-Session Cure
To experience the power of Autologous Micrograft Therapy, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

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Autologous Fibroblast Therapy involves harvesting a tiny tissue sample from behind your ear, multiplying your own collagen-producing cells (fibroblasts) in a GMP laboratory, and re-injecting millions of them into your skin. It is a biological time machine designed to increase your skin’s regenerative capacity naturally.
⚠️ Important Note
This is NOT the Plasma Pen procedure. Often confused by name, the Plasma Pen is a device that burns the skin surface. Our therapy is a cellular bio-engineering protocol involving tissue culture and injection, performed by a medical doctor.
What Is Autologous Fibroblast Therapy?
Over time, the number of fibroblast cells—the factories that produce collagen and elastin—declines. This therapy replenishes that reserve. We take young, sun-protected cells from behind your ear, expand them in a laboratory, and reintroduce them to your face, neck, or hands.
The Key Difference:
● Fillers:
● Fillers: Used to add volume or shape.
● Autologous Fibroblast: Restores the skin’s structure (Like rebuilding the foundation).
Why Is It a “Biological Investment”?
This treatment is not off-the-shelf. It is 100% personalized.
1. Fully Autologous: Both the cells and the serum used to culture them come from you. Zero risk of allergy.
2. Multiplication: The 4–6 week lab process turns a tiny tissue sample into tens of millions of active, youthful cells ready to work on your skin.
Who Is This Treatment For ?
● Long-Term Residents/Expats in Istanbul: Since the protocol requires 2-3 sessions spaced over months, it is ideal for those living in or frequently visiting Istanbul.
● Natural Beauty Seekers: Patients who want to look younger without changing their facial expressions or volume.
● Acne Scar Patients: One of the most effective biological treatments for filling deep, pitted acne scars naturally.
The Process: A 4-Stage Journey
1. Holistic Preparation: Healthy cells come from a healthy body. Dr. Ömer Fatih Şahin reviews your blood work (Iron, Vitamin D, etc.) and may recommend supplements or IV therapy to optimize your cell quality before the biopsy.
2. Biopsy (15 Minutes): Under local anesthesia, a small tissue sample (3-4 mm) is taken from behind the ear. It is painless and requires no stitches.
3. Laboratory Expansion (4–6 Weeks): Your tissue is sent to a Ministry of Health-approved GMP lab. Your fibroblasts are separated and multiplied into millions.
4. Injection Protocol (2-3 Sessions): The produced cells are injected into the skin in 2-3 sessions, spaced 3-4 weeks apart. Approximately 20-50 million fresh cells are delivered to the skin in each session.
Frequently Asked Questions (FAQ)
1. Autologous Fibroblast vs. Alloblast (Newborn Cells): Which is better?
● Alloblast: Uses cells from a donor (newborn). While potent, it involves introducing foreign
DNA into your body.
● Autologous Fibroblast: Uses 100% your own cells. The risk of allergic reaction or immune
rejection is considered extremely low. It is the safest biological route for those who prioritize
biocompatibility.
2. I am over 50. Are my cells too old to work? Not at all. We harvest tissue from behind the
ear—an area protected from sun damage and aging. The cells there are biologically younger than
your facial cells. Furthermore, the laboratory process selects and multiplies only the healthiest, most
active cells to re-inject.
3. Will this make my face look puffy? No. This is not a dermal filler. It does not add artificial volume
or change your facial features. It rebuilds the skin’s internal structure, resulting in firmer, tighter skin
without the pillow face look.
4. Is there a cancer risk? No. Fibroblasts are mature cells, not embryonic stem cells. They do not
have the capacity to mutate into tumors. The laboratory process only multiplies their number; it does
not alter their DNA. It is a strictly controlled, safe medical procedure.
5. Is it effective for Acne Scars? Yes. It is one of the gold-standard biological treatments for deep
acne scars. By injecting new collagen-producing cells directly into the scars, we help rebuild the tissue
from underneath, smoothing the skin surface naturally.
6. When will I see results? This is a slow beauty process. You may see a glow after the first month,
but the real structural remodeling (tightening and lifting) peaks around Month 6 after the collagen
network has been rebuilt.
7. How long do the results last? The cells we inject continue to live in your skin. It effectively turns
back your skin’s biological clock by several years. Results are typically enjoyed for 3–5 years,
depending on your lifestyle.
8. How is it different from SVF (Stem Cell) Therapy? SVF is a same-day procedure utilizing fat
tissue. Autologous Fibroblast takes weeks of lab culture to produce pure collagen-building cells. If
your main concern is specific scar repair or pure collagen loss, Fibroblast is extremely targeted.
9. Where can it be applied? Apart from the face, it is excellent for the neck, décolleté, and
hands—areas that often reveal age the most.
10. Can I fly back home between sessions? Since the protocol requires 3 sessions spaced 3-4
weeks apart, it is best suited for expats living in Istanbul or patients who can travel frequently. If you
need a one-visit solution, ask us about SVF Therapy instead.

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Exosome Skin Therapy is an advanced regenerative protocol that delivers biological repair signals to skin cells. At our clinic in Nişantaşı, Istanbul, we offer customized treatments using either Human-Derived (MSC) or Plant-Derived (Phyto) exosomes, depending on your skin’s specific needs for anti-aging, hydration, or barrier repair.
Exosome Skin Therapy
Skin aging is not just about losing collagen; it’s about the slowdown of cellular communication. Our cells stop sending “repair” signals to each other effectively.
Exosome Therapy is the most advanced biotechnology designed to restart this communication by delivering billions of “youth and repair messages” directly to your skin cells.
What Are Exosomes & How Do They Work?
Exosomes are not stem cells. They are nano-sized messenger packets released by stem cells or plants. They contain thousands of active regenerative molecules:
● Growth Factors
● Peptides & Proteins
● mRNA & miRNA (Genetic signals)
When applied to the skin (via mesotherapy or microneedling), these exosomes dock into your fibroblast cells and instruct them to:
1. Produce: Increase Collagen, Elastin, and Hyaluronic Acid synthesis.
2. Calm: Reduce chronic inflammation (redness/sensitivity).
3. Repair: Heal the skin barrier and reduce pigmentation.
Two Types of Exosomes Used in Our Clinic
Dr. Ömer Fatih Şahin does not believe in a one-size-fits-all approach. Based on your skin analysis, we select the most suitable source:
1. Human-Derived (MSC) Exosomes
● Source: Ethically harvested from neonatal Umbilical Cord Mesenchymal Stem Cells.
● Best For: Deep repair, significant anti-aging, loss of elasticity, and acne scarring.
● Effect: Powerful cellular regeneration and structural improvement.
2. Plant-Derived (Phyto) Exosomes
● Source: Extracted from high-antioxidant plants (e.g., Rose, Centella) using biotechnology.
● Best For: Dullness, dehydration, pigmentation (dark spots), Rosacea, and preventative care (pre-juvenation).
● Effect: Intense hydration, brightening, and anti-inflammatory support.
MSC exosomes are produced in GMP (Good Manufacturing Practice) certified laboratories, ensuring maximum safety and purity.
Who Is a Candidate?
Following a medical evaluation, this treatment is suitable for patients who want to treat:
● Fine lines, wrinkles, and skin laxity.
● Dull, tired, and dehydrated skin.
● Hyperpigmentation (Sun spots, Melasma).
● Acne Scars and enlarged pores.
● Rosacea (Redness) or sensitive skin conditions.
● Those seeking a natural, biological alternative to synthetic fillers.
Treatment Process in Istanbul
1. Consultation: Dr. Ömer Fatih Şahin analyzes your skin condition to decide whether MSC or Plant exosomes (or a combination) will yield the best results for you.
2. Application: After cleansing and applying a topical anesthetic, the exosome serum is delivered into the skin using mesotherapy (fine needles) or following a microneedling session. The procedure takes 20–30 minutes.
3. Protocol: For optimal results, a course of 3 to 5 sessions spaced 2–4 weeks apart is typically recommended.
Frequently Asked Questions (FAQ)
1. Which one should I choose: Human or Plant Exosomes? Your doctor will guide you. Generally, MSC (Human) is chosen for deep anti-aging and scarring, while Plant exosomes are excellent for glow, hydration, and uneven skin tone.
2. Is this a stem cell transplant? No. It is an acellular (cell-free) therapy. We use the pure signaling molecules produced by cells, not the live cells themselves. This eliminates the risk of rejection.
3. How is it different from Salmon DNA or Skin Boosters? Traditional boosters provide ingredients (vitamins,peptides, HA). Exosomes provide the instructions on how to use those ingredients to repair the tissue. It is a smarter, more advanced technology.
4. When will I see results? You may notice an immediate glow and hydration after the first session. However, true collagen remodeling and structural changes become visible after 3 months.
5. What is the cost of Exosome Therapy in Istanbul ? Prices vary depending on the type of exosome (MSC vs. Plant) and the number of sessions. Treatment in Turkey offers premium quality at significantly more affordable rates than in the EU/UK.
Planning Your Skin Treatment in Istanbul
Exosome therapy is an ideal procedure for international visitors as it has minimal downtime.
● Treatment Time: Only 30 minutes. You can return to your social life almost immediately.
● Aftercare: Slight redness may occur for a few hours. Avoid direct sun and heavy makeup for 24 hours.
● Location: Our clinic is in the heart of Nişantaşı, Istanbul’s luxury fashion and dining district.
You can combine your treatment with a shopping trip or a nice dinner.

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Alloblast is an advanced regenerative treatment that uses GMP-manufactured allogeneic fibroblast cells derived from day-1 neonatal tissue to stimulate the production of collagen, elastin, and the extracellular matrix. Unlike traditional methods, this is not a stem cell treatment but a direct infusion of worker cells that rebuild the skin. Because the procedure is completed in a single session,
Alloblast is the ideal anti-aging solution for international patients visiting Istanbul for short medical trips. At our Nişantaşı clinic, we integrate Alloblast into personalized longevity and aesthetic protocols, ensuring safe and high-standard biological repair.
What Is Alloblast?
Alloblast is an allogeneic fibroblast suspension produced from the foreskin tissue of 1-day-old newborns. These cells are expanded under strictly controlled conditions in GMP-certified (Good Manufacturing Practices) and Ministry of Health-approved Tissue Banks.
Important Distinction: Alloblast is an ATMP (Advanced Therapy Medicinal Product). It is not a stem cell therapy; rather, it is the application of young, dynamic fibroblasts—the cells responsible for maintaining skin structure.
Why Neonatal Fibroblasts?
Neonatal cells are biologically superior to adult cells because they possess:
● Long Telomeres: Maximum capacity for cell division and renewal.
● High Mitochondrial Activity: Superior energy production for tissue repair.
● Low Oxidative Stress: Zero exposure to environmental toxins or UV damage.
● Strong ECM Capacity: They produce collagen and elastin much faster than older cells.
Why Does Skin Age?
As we age, the number of fibroblasts in our skin decreases, and the ECM (Extracellular Matrix) weakens. This structural decline leads to wrinkles, loss of elasticity, sagging, and uneven skin tone.
Alloblast reverses this process by injecting millions of fresh fibroblasts into the dermis. These cells immediately begin to:
1. Increase Type I and Type III Collagen production.
2. Enhance Elastin synthesis for tighter skin.
3. Promote Neovascularization (new blood vessel formation) to nourish the skin.
Alloblast vs. Fibrocell (Autologous)
International patients often ask: “Should I use my own cells (Autologous) or Alloblast?” For medical tourists, Alloblast offers significant advantages:
1. FIBROCELLTM (Autologous / Your Own Cells)
● Source: Requires a biopsy from behind your ear.
● Wait Time: 3-6 weeks needed for lab production.
● Visits: Requires multiple clinic visits (Biopsy + Injections).
● Cell Age: Same age as the patient (e.g., 50 years old).
2. ALLOBLASTTM (Allogeneic / Neonatal Cells)
● Source: Ready-to-use neonatal tissue; no biopsy needed.
● Wait Time: Available immediately (upon booking).
● Visits: Completed in a single session.
● Cell Age: 0 years old (Peak biological potential).
How Is It Performed? (Step-by-Step)
At our clinic in Nişantaşı, we prioritize patient comfort and sterility.
1. Preparation: The skin is cleansed with a sterile solution. Topical anesthesia can be applied if requested.
2. Product Preparation: The cold-chain (+4 C ) preserved vial is brought to the treatment room and drawn into 1cc Luer-Lock syringes using a 21G needle.
3. Injection: Using very fine 30G needles, the product is injected using the intradermal papule technique.
4. Technique: Approximately 100–200 μl is deposited per point. Note: We do not use cannulas or linear injection techniques for this specific treatment.
5. Duration: The entire procedure takes only 30 minutes.
Why Alloblast Is Ideal for International Patients
Alloblast is one of the most requested treatments by our international guests visiting Istanbul for the following reasons:
● Single Session: Unlike many treatments that require weekly visits, Alloblast is a one-and-done procedure.
● Zero Downtime: You can return to sightseeing or business meetings immediately (mild redness fades in 1-3 hours).
● High Safety Profile: Produced in GMP-certified labs, ensuring international safety standards.
● Combination: It can be easily combined with other longevity treatments like Exosomes or IV Therapies during your visit.
Post-Procedure Instructions
● First 24 Hours: Do not allow water to touch the treated area.
● First 3 Days: Avoid using cosmetics/makeup and stay away from hot environments (such as Turkish baths, saunas).
● First Week: Avoid heavy cardio exercises and strenuous physical activity.
● Appearance: Post-procedure papules (tiny bumps) and slight redness may occur; this typically resolves spontaneously within 24 hours.
● Timeline of Results: Vitality and radiance begin to appear after 1 month. Significant biological repair and tightening become apparent after 6-8 weeks, reaching optimal levels by the 6th month, with continued improvement for 9-12 months.
● First 3 Months: Deep tissue laser treatments should be avoided.
Frequently Asked Questions (FAQ)
Is Alloblast a stem cell treatment?
No. Alloblast is a specific fibroblast therapy. While both are regenerative, Alloblast focuses directly on replenishing the cells that produce collagen.
How many sessions do I need?
For the vast majority of patients, one session is sufficient due to the high potency of neonatal cells.
Is it safe?
Yes. The product is biocompatible and produced under strict GMP and Ministry of Health regulations. The risk of allergic reaction is extremely low as the cells are immunologically privileged.
How long do the results last?
The biological repair initiated by Alloblast typically sustains skin quality for 9–12 months. Since it reverses cellular aging, your skin will remain in better condition than if you hadn’t had the treatment.
Q: Can I get this done during a 2-day trip to Istanbul ?
A: Absolutely. However, please note that we require at least 24 hours to order the specific product from the laboratory, so advance booking is essential. The procedure fits perfectly into a short schedule, and there are no restrictions on air travel, meaning you can safely fly back on the same day as your treatment.

2026 © Ömer Fatih Şahin - Aesthetic & Wellness

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