Biostimulants - Liquid Facelift arşivleri - Uzm. Dr. Ömer Fatih Şahin

Irregular skin texture, enlarged pores, and especially persistent post-acne scars are among the most challenging concerns in aesthetic medicine. Juvelook, an award-winning Korean innovation, is a hybrid biostimulator that combines PDLLA (Poly-D,L-Lactic Acid) and Hyaluronic Acid (HA) to go beyond simple hydration. It focuses on the biological “reconstruction” of the skin at a cellular level.

The defining advantage of Juvelook is its ability to repair the skin’s collagen architecture from the “inside out,” creating a smooth and refined dermal structure.

Regenerative Pathway: Cellular Induction and Dermal Remodeling

Juvelook’s dual-action technology is designed for deep structural skin renewal:

Hybrid Composition: A precise blend of 5 mg PDLLA (the collagen trigger) and 12.5 mg non-crosslinked HA (for immediate hydration).
Cellular Stimulation: Once injected, Juvelook stimulates fibroblast cells to initiate the production of new collagen (Neocollagenesis).
Biodegradability & Safety: Its micro-particles, sized between 20-40 microns, are gradually broken down into water and carbon dioxide, leaving the body entirely. What remains is a fresh, healthy framework of your own natural collagen fibers.

Why Choose Juvelook for Acne Scars?

While patients often search for “fillers” for acne scars, Juvelook is fundamentally different; it is a scar remodeler.

Atrophic Scar Treatment: For “boxcar” and “rolling” scars caused by collagen loss, Juvelook fills the deficit from within. It physically lifts the base of the scar to level the skin surface.
Enhanced Skin Quality: Scarred tissue is often rigid and lacks elasticity. Juvelook increases dermal density in these areas, restoring the skin’s natural flexibility.
Long-Term Biological Repair: Unlike standard HA fillers that eventually dissolve, the collagen network built by Juvelook becomes part of your own tissue, providing long-lasting structural improvement.

Facial Rejuvenation and the “Glass Skin” Effect

When applied across the entire face, Juvelook optimizes the skin’s general “architecture”:

Pore Minimization: As the collagen matrix strengthens, the diameter of enlarged pores visibly shrinks.
Refined Texture: It eliminates micro-imperfections and “crepey” fine lines, delivering the coveted “Glass Skin”
Natural Aesthetics: Juvelook enhances skin quality and elasticity without altering the natural contours of your face.

Technical Comparison: The Juvelook Difference

Feature	Juvelook (Hybrid PDLLA)	Sculptra/Lanluma (PLLA)
Particle Size	20-40 Microns (Ultra-Fine)	40-80 Microns (Dense)
Massage Protocol	Not Required	Sculptra: 5 Days / Lanluma: 14 Days
Primary Goal	Acne Scars, Texture Quality	Deep Volume & Lifting
Injection Layer	Upper Dermis (Superficial)	Deep Dermis / Subcutaneous

Frequently Asked Questions (FAQ)

Can Juvelook completely remove acne scars?

Juvelook is one of the most effective biological treatments for atrophic (pitted) scars. It significantly reduces scar depth and smooths the skin surface. For optimal results, a protocol of 3 sessions is typically recommended.

Is there a risk of nodules (lumps) after treatment?

Juvelook’s patented spherical molecule structure and high solubility minimize this risk. Unlike older generation polylactic acids, it does not require an aggressive post-treatment massage protocol.

Is Juvelook a dermal filler?

No, it is a biostimulator. While the HA content provides immediate radiance, its primary goal is to stimulate your body to produce its own collagen for long-term repair.

When will I see results and how long do they last?

Hydration and glow are visible shortly after the procedure. However, structural collagen repair begins after the 4th week. The revitalized skin structure usually maintains its resilience and quality for a duration of 1.5 to 2 years.

How many sessions are needed?

For acne scar remodeling and skin texture improvement, a series of 3 sessions spaced 4 weeks apart is the gold standard protocol.

Hip dips are natural, inward curves on the sides of the hips and are not a medical condition. For patients seeking a smoother silhouette without surgery, Dr. Ömer Fatih Şahin’s clinic in Nişantaşı, Istanbul, offers advanced biostimulation using PLLA (Poly-L-lactic acid) products like Lanluma and Sculptra. Instead of instantly filling the area with artificial volume or undergoing surgical fat transfer, this approach stimulates your body’s own collagen production for a gradual, natural, and long-lasting contour improvement.

What Are Hip Dips and Why Do They Occur?

Hip dips (also known as violin hips) are inward depressions along the side of your body, just below the hip bone. They are related to the shape of your pelvis, the width of your hips, the position of your femur, and the natural distribution of your fat and muscle.

The most important thing to know is: Hip dips are entirely normal and not a disease.

They are frequently seen in very athletic and slim individuals.
While building gluteal muscle through exercise can slightly soften the appearance, it often cannot completely change the anatomical bone structure.

When evaluating hip dips, the focus should go beyond the simple addition of volume and instead center on the patient’s desired outcome: maximum projection, a softer transition, or improved tissue quality.

What is PLLA (Poly-L-Lactic Acid)?

PLLA is an advanced biostimulator used in aesthetic medicine. Unlike traditional dermal fillers that just take up space, PLLA acts as a “seed” to wake up your body’s fibroblast cells, making them produce fresh collagen.

Lanluma: Officially described as a collagen-stimulating injection that improves skin quality, adds volume, and enhances contours in selected areas. Smoothing out hip dips and enhancing buttocks shape are among its primary body indications.
Sculptra (Galderma): By the end of 2025, Galderma expanded its use in various body areas, including the gluteal region, with EU MDR certification. Galderma emphasizes progressive improvement, skin firmness, lifting effects, and contour optimization.

Why Choose PLLA for Hip Dips? (The Istanbul Approach)

At our clinic in Turkey, we don’t believe in a “one-size-fits-all” approach. However, for many international patients, PLLA-based biostimulation stands out over traditional Hyaluronic Acid (HA) fillers or surgical fat grafting (BBL) for 4 main reasons:

Natural & Gradual Transformation: PLLA avoids the “overfilled” look. It provides natural-looking, progressive results that integrate perfectly with your body.
Skin Quality & Firmness: It’s not just about volume. Sculptra and Lanluma significantly improve skin quality, firmness, and provide a subtle lifting effect to the body.
Non-Surgical (Minimal Downtime): This is crucial for our international patients. Fat grafting requires liposuction, anesthesia, and a long recovery. PLLA injections offer a non-surgical alternative with minimal downtime, allowing you to enjoy your trip to Istanbul.
Biological Support: According to a 2025 expert review, PLLA performs exceptionally well in the gluteal region not by creating massive reshaping, but by providing superior lifting effects and skin quality improvements.

Treatment Comparison: PLLA vs. Fat Grafting

Feature	PLLA (Lanluma / Sculptra)	Surgical Fat Grafting (BBL)
Mechanism	Stimulates your own collagen	Transfers fat from another body part
Procedure Type	Non-surgical (Injections)	Surgical (Requires Liposuction)
Result Timeline	Gradual and progressive	Immediate volume (with initial swelling)
Main Advantage	Natural feel, skin firming, no surgery	Ability to achieve massive volume

The Procedure & What to Expect

Who is the Ideal Candidate?

This treatment is ideal for individuals with moderate contour irregularities who desire a “soft transition” rather than extreme projection, and who prefer a non-surgical route. However, patient selection is key; literature notes that results can vary based on body composition, and patients with significantly low or high Body Mass Index (BMI) might experience lower satisfaction rates.

When Will I See Results?

Results are not instant. The effect develops gradually over time. While volumetric improvement for moderate hip dips is achievable, the biological response in body areas is slower than the face. Peak effects are often seen 3 to 6 months after the initial session.

How Many Sessions Do I Need?

The number of sessions is not fixed. It depends on your subcutaneous tissue, the severity of the dip, and your body’s biological response. We do not promise the exact same outcome for everyone; personalized assessment by Dr. Şahin is required.

Frequently Asked Questions (FAQ)

Are hip dips a medical condition?

No. They are an anatomical body shape related to your bone structure. However, if they affect how clothing fits or cause aesthetic concern, treatment can be requested.

How does PLLA work for hip dips?

PLLA is a biostimulator. It doesn’t just artificially fill the gap with gel. It stimulates your tissue to produce collagen, gradually thickening the skin and creating a balanced contour naturally.

Will I see the results before flying back home?

You will see some initial volume due to the sterile water used to mix the product, but this subsides in a few days. The true magic (collagen production) takes weeks to begin, meaning your results will gradually improve over the months after you return home.

How long do the results last?

Because PLLA stimulates your own natural collagen, the results are much longer-lasting than traditional HA fillers. Patients typically enjoy results lasting up to 2 years or more, gracefully fading as the natural aging process continues.

What is the difference between this and Hyaluronic Acid (HA) fillers?

HA fillers are gels that provide instant volume but degrade relatively quickly in body areas (usually 9-12 months). PLLA is a “collagen seed”; it doesn’t give instant massive volume but biologically firms and thickens your own tissue over time.

Is the procedure painful?

It is highly tolerable. We use topical numbing creams, and a local anesthetic (Lidocaine) is mixed directly into the PLLA product. Patients usually feel only mild pressure.

What is recovery like? (The Massage Protocol)

There is minimal downtime, making it great for medical tourists. You may experience mild swelling, tenderness, or bruising for a few days. Crucially, you must follow the “Massage Protocol” advised by Dr. Şahin (e.g., massaging the area 5 times a day, for 5 minutes, for 5 days) to ensure the product distributes evenly and prevents nodules.

When can I exercise or fly?

You are generally safe to fly the next day. We recommend avoiding heavy lower-body exercises and excessive sweating for about 5-7 days post-treatment.

Is this an alternative to surgical fat grafting?

Yes, for many patients it is a superior non-surgical alternative. It is especially perfect for patients who do not want surgery, do not have enough harvestable fat for liposuction, or simply want a sophisticated, natural contour rather than an exaggerated look.

Will it feel natural to the touch?

Absolutely. Because the added volume is your own newly generated collagen, it looks, moves, and feels exactly like your natural tissue.

Who is not a good candidate?

Patients expecting dramatic, massive volume in a single day, those with active autoimmune diseases, pregnant/nursing women, or individuals with unrealistic expectations are not suitable candidates. A thorough consultation is always required.

In the evolving world of aesthetics, the pursuit of “natural volume” and “biological lifting” has standardized the use of advanced polylactic acid technologies. As a premier representative of this category, Lenisna is a high-performance hybrid restructurer that utilizes the synergy of high-density PDLLA (Poly-D,L-Lactic Acid) and Hyaluronic Acid (HA).

Lenisna provides a specialized protocol designed to tighten facial contours while repairing deep tissue loss by stimulating the body’s endogenous collagen production.

Structural Bio-Matrix: Functional Dermal Engineering

Based on technical data regarding Lenisna, its regenerative pathway within the dermal layers can be defined as follows:

Hybrid Formulation: Each vial contains a potent concentration of 170 mg PDLLA and 30 mg Hyaluronic Acid.
Dual-Phase Induction: Upon application, the HA component provides immediate hydration and subtle shaping; meanwhile, the primary PDLLA micro-particles initiate a neocollagenesis (new collagen synthesis) process that unfolds over several months.
Architectural Molecular Structure: The macro-particles, sized between 40-80 microns, create a structural scaffold within the deep dermis and subcutaneous tissue, reinforcing the skin’s internal framework.

Targeted Applications: Ideal Treatment Zones

Lenisna is considered an “architectural” support product, making it the preferred choice for areas requiring deeper structural volume:

V-Line and Jawline: Defining the jawline and lifting sagging tissues for a sharper contour.
Temples and Mid-Face: Restoring volume to hollow temples and sunken cheeks with a natural appearance.
Deep Folds: Biologically softening pronounced nasolabial folds (smile lines).
Body Contouring: Providing collagen support for areas experiencing elasticity loss, such as the abdomen, inner arms, and above the knees.

Market Analysis: Polylactic Acid Brand Comparison

There are various technological approaches to polylactic acid treatments globally. The differences between the market’s leading players are summarized below:

Brand and Technology Matrix

Feature	Sculptra	Lanluma X	Lenisna
Molecule Type	Pure PLLA	Pure PLLA	PDLLA + HA (Hybrid)
Clinical Approval	FDA Approved	CE Certified	CE Certified
Massage Duration	5 Days (5-5-5 Rule)	14 Days (10 min, 2x daily)	Not Required
Application Area	Face & Body	Face & Body	Face & Body
Primary Effect	Natural Volume & Repair	Deep Repair & High Body Volume	Lifting & Biological Restoration

Critical Note: For PLLA-based products (Sculptra and Lanluma), a consistent post-treatment massage is vital to ensure the even distribution of crystalline particles and prevent nodule formation. In contrast, Lenisna (PDLLA-based) utilizes spherical particle technology, which integrates seamlessly into the tissue without the need for a mandatory massage protocol.

Frequently Asked Questions

Do I need to massage the treated area after Lenisna?

No. Due to Lenisna’s specific molecular structure and its distribution mechanism within the tissue, it does not require the rigorous, multi-day massage protocols (such as Sculptra’s 5-5-5 rule) typically associated with older polylactic acids.

Why do Sculptra and Lanluma require post-treatment massage?

Both products are composed of PLLA (Poly-L-Lactic Acid). To prevent these crystalline particles from clumping and to ensure a smooth collagen network is built, a clinical protocol of massaging 5 times a day for 5 days is essential.

Which product is FDA-approved?

Sculptra is the only polylactic acid product with the longest clinical history and FDA approval. Lenisna and Lanluma are reliable alternatives with international certifications (such as CE) that meet global medical standards.

Which product is preferred for body skin laxity?

Sculptra and Lanluma are high-volume options that have been used for years, particularly for buttocks and body contouring. Lenisna is generally preferred for body areas when the primary goal is “skin tightening and biological lifting.”

When will the results peak and how long do they last?

Once the collagen synthesis process is established, the biological rejuvenation achieved through this process maintains its structural integrity for a period of up to 24 months, depending on the patient’s lifestyle and skin quality.

Sculptra is an FDA-approved biostimulator treatment that activates your skin’s natural power to produce collagen, restoring facial volume and improving skin quality for up to 2 years. Unlike traditional fillers, it offers gradual, natural-looking results without the “puffy” look. At our clinic in Nişantaşı, Istanbul, we offer premium Sculptra treatments tailored for international patients seeking world-class aesthetic care.
What is Sculptra?
● Sculptra is an injectable collagen-stimulating treatment formulated with PLLA. It works deep within the dermis to help revitalize collagen production and restore your skin’s inner structure. It is the ideal choice for patients who want to treat the underlying cause of facial aging rather than just the symptoms.
How Does It Work?
Sculptra does not just “fill” a wrinkle; it rebuilds the skin matrix.
1. Stimulation: PLLA microparticles are delivered into the skin to activate collagen production.
2. Collagen Growth: These particles stimulate fibroblasts to produce new collagen strands.
3. Restoration: Over time (4-6 weeks), the skin becomes firmer, thicker, and more youthful.
Scientific Fact: Clinical studies show that Sculptra can increase Type-1 Collagen levels by 66.5% after just 3 months. This makes it a powerful anti-aging foundation for your skin.
Why Choose Sculptra in Istanbul?
Many international patients choose Istanbul for Sculptra treatments due to:
● High-Quality Care: Treatment by experienced medical doctors using FDA-approved products.
● Cost-Effectiveness: Premium aesthetic treatments at competitive prices compared to Europe or the US.
● Location: Our clinic is located in Nişantaşı, the luxury fashion and medical district of Istanbul, perfect for a combined medical & leisure trip.
Sculptra vs. Hyaluronic Acid Fillers
It is important to understand the difference to choose the right treatment for your needs:
● Hyaluronic Acid (HA) Fillers: Provide immediate volume. They are gels that fill space. Best for specific contouring (lips, nose). Results last 6–18 months.
● Sculptra: Provides gradual, natural restoration. It is a collagen stimulator. Results appear over weeks and last 24+ months. Best for overall skin tightening and natural rejuvenation.
The Procedure & Recovery
The procedure is quick, taking only 30-45 minutes, making it a perfect “lunchtime procedure” that won’t disrupt your holiday.

● Downtime: Minimal. You can return to exploring Istanbul immediately.
● The “5-5-5” Rule: You must massage the treated area for 5 minutes, 5 times a day, for 5 days. This is crucial for distributing the product evenly.
● Restrictions: Avoid saunas, Turkish hamams, and direct prolonged sun exposure for the first 24-48 hours. Flying home the next day is generally safe.
Frequently Asked Questions (FAQ)
What happens if a patient is not satisfied with the results of Sculptra? No, unlike HA fillers,
Sculptra cannot be dissolved immediately with an enzyme. Because it builds your own collagen, the
results are very natural, but this makes it essential to choose an experienced doctor for the
application.
How many sessions do I need? For optimal results, we typically recommend 2 to 3 sessions,
spaced 4-6 weeks apart. However, even a single session provides significant collagen stimulation.
Can I fly after Sculptra? Yes, it is safe to fly after the procedure. We recommend staying hydrated
and avoiding alcohol on your flight to minimize swelling.
Is Sculptra safe? Yes, Sculptra is FDA-approved and has been used safely worldwide since 1999. It
is biocompatible and biodegradable.
When will I see the results? Sculptra is a marathon, not a sprint. You will see a “Sculptra Glow”
starting around week 6, with full results maturing over 3-6 months.

Radiesse is an FDA-approved calcium hydroxyapatite (CaHA) biostimulator engineered to restore skin quality, elasticity, and firmness by triggering the body’s own collagen production. It is not a volumizing filler but a regenerative treatment. At our clinic in Nişantaşı, Istanbul, we specialize in “Hyperdilute Radiesse” protocols to tighten loose skin on the face, neck, and body, offering a premium experience for our international patients.
What Is Radiesse?
Radiesse is a powerful injectable biostimulator made of Calcium Hydroxyapatite (CaHA) microspheres. Unlike traditional Hyaluronic Acid fillers that simply add volume, Radiesse works biologically to rejuvenate the skin’s architecture.
Key Benefits:
● Collagen Stimulation: Supports the skin’s natural regeneration process by promoting fibroblast-mediated Type I and Type III collagen production over time.
● Skin Tightening: Improves dermal thickness and smooths crepey texture.
● Non-Volumizing: Ideal for patients who want to avoid the “puffy” or “over-filled” look.
Which Treatment Is Right for You?
To help you decide, here is how Radiesse compares to other popular injectable treatments available in our clinic:
1. Radiesse (CaHA)
● Primary Goal: Skin tightening, structural improvement, and long-term quality.
● Mechanism: Biostimulation (Active collagen production).
● Longevity: 12–18 Months.

● Volume Effect: None / Minimal (when used in Hyperdilute form).
2. Dermal Fillers (Hyaluronic Acid)
● Primary Goal: Restoring lost volume and shaping contours (e.g., Lips, Cheeks).
● Mechanism: Filling hollow spaces physically.
● Longevity: 6–12 Months.
● Volume Effect: High / Immediate volume.
3. Mesotherapy / Skin Boosters
● Primary Goal: Deep hydration and surface glow.
● Mechanism: Moisture retention.
● Longevity: 3–6 Months.
● Volume Effect: None.
Why Does Skin Age? How Does CaHA Help?
As we age, fibroblast activity slows down. This leads to a weakened Extracellular Matrix (ECM),
resulting in sagging and crepey skin. When Radiesse is injected, the CaHA microspheres act as a scaffold. They physically stimulate
fibroblasts to “wake up” and start producing new collagen. Histological studies confirm that this creates a denser, younger-looking dermis.
What Is Hyperdilute Radiesse?
Hyperdilute Technique:
The hyperdilute technique is designed to prioritize skin quality improvement by enhancing tissue diffusion rather than volumization. This transforms it from a thick filler into a spreadable, skin-rejuvenating wash.
● Targeted Tightening: Perfect for larger areas like the neck or décolletage.
● Natural Results: No risk of lumps or unnatural volume changes.
● Versatility: Can be used on the body as well as the face.
Treatment Areas
● Neck & Décolletage: Smooths “Turkey neck” and horizontal chest wrinkles.
● Mid/Lower Face: Tightens skin without changing facial shape.
● Hands: Restores volume to bony hands and hides visible veins.
● Body: Inner arms and abdomen (post-pregnancy laxity).
Do We Use Radiesse for Jawline?
No. Transparency is our priority.
In my clinical practice, I do not use Radiesse for volumetric jawline contouring. I strictly use it as a skin
quality agent. If a patient requires jawline definition or chin projection, I prefer Hyaluronic Acid (HA)
fillers for safer, reversible, and more precise structural results.
Plan Your Visit: Nişantaşı & Logistics
For our international patients, we ensure a seamless experience:
● Location: Our clinic is located in Nişantaşı, Istanbul’s most prestigious fashion and lifestyle
district. We are walking distance from luxury hotels like The St. Regis and The Stay.

● Short Stay: Radiesse is a “lunchtime procedure.” You can have the treatment and
immediately enjoy shopping or dining in the neighborhood.
● Flight Safety: You can safely fly the next day. The clinic is approximately 45 minutes from
Istanbul Airport (IST).
Powerful Combinations
Radiesse is effective on its own, but can be combined with other treatments for holistic results:
● Botox: While Radiesse tightens the skin structure, Botox relaxes dynamic wrinkles for a
smoother look.
● Mesotherapy / Skin Boosters: Radiesse builds the collagen scaffold, while skin boosters
provide deep hydration and surface glow.
Our Clinical Approach & Comfort
Patient safety and comfort are our top priorities.
● Pain Management: With a background in Anesthesiology, Dr. Şahin ensures that pain
management is optimized, making the procedure virtually painless.
● Customized Protocols: We avoid “one-size-fits-all” approaches; protocols are strictly
customized based on skin thickness and aging grade.
FAQ (Frequently Asked Questions)
1. Is Radiesse a filler? Technically yes, but in our clinic, we utilize it primarily as a biostimulator to
improve structure rather than add bulk volume.
2. Can Radiesse be dissolved? Unlike Hyaluronic Acid fillers, Radiesse cannot be dissolved
immediately with an enzyme. This is why choosing an expert physician is crucial for safety and
aesthetic success.
3. How many sessions do I need? Treatment Sessions:
Visible skin quality improvement can often be observed after a single session, although treatment
response varies according to individual skin characteristics. For severe laxity, a second session may
be recommended after 2-3 months.
4. When will I see results? You may see an immediate glow, but the real structural improvement
begins at 4 weeks as new collagen forms, peaking around the 3-month mark.
5. Is it painful? No. We mix the product with lidocaine (local anesthetic), and use a gentle cannula
technique to ensure minimal discomfort.
6. Can I fly after the treatment? Yes, it is safe to fly the next day. There are no pressure-related
restrictions for this treatment.
7. How long does the effect last? Results typically last between 12 to 18 months, depending on
your lifestyle and skin type.
8. Are there any side effects? Common side effects include mild swelling or bruising, which usually
resolves within a few days. The Hyperdilute technique minimizes these risks significantly compared to
standard fillers.

Lanluma is an injectable Poly-L-Lactic Acid (PLLA) biostimulator. Unlike traditional fillers that simply add volume, Lanluma works deep within the skin to activate your body’s natural collagen production, creating long-lasting volume, texture improvement, and tightness. At our clinic, Specialist Dr. Ömer Fatih Şahin uses Lanluma to sculpt the body (Non-Surgical BBL) and rejuvenate the face without the “puffy” look associated with overfilled hyaluronic acid.
Lanluma V vs. Lanluma X: Targeted Solutions
Depending on your goals, we use specialized forms of Lanluma:
1. Lanluma V (Facial Rejuvenation) Designed for correcting deep lines and restoring lost facial
volume.
● Best For: Sunken cheeks, temples, and improving overall skin quality.
● The Result: A youthful, firmer look that evolves naturally over months. No one will know you
“had work done.”
2. Lanluma X (Body Contouring) A game-changer for non-surgical body sculpting.
● Non-Surgical BBL: Adds projection and roundness to the buttocks without surgery or fat
transfer.
● Hip Dips: Fills the indentations on the sides of the hips for an hourglass silhouette.
● Cellulite Reduction: Thickens the skin structure, effectively smoothing out cellulite dimples
on the thighs and buttocks.
● Arm & Knee Rejuvenation: Helps enhance skin firmness and texture in areas prone to laxity.
The Timeline: Patience Pays Off
PLLA is not an instant fix; it is a bio-process.
1. Immediate: You will see fullness from the water in the injection, which subsides in a few days.
2. Weeks 4-8: Your body starts producing new collagen fibers around the PLLA particles.
3. Month 3: The “real” volume and tightening effect become visible.
4. Longevity: Results typically last 2 to 3 years, significantly longer than HA fillers.
The Golden Rule: Massage
To ensure a smooth result, patient compliance is key. You must massage the treated area:
● Twice a day
● For 10 minutes
● For 2 weeks This helps distribute the product evenly for a perfect finish.
Frequently Asked Questions (FAQ)
● Question: Can lumps or nodules form?
● Answer: While rare, small palpable areas may form under the skin. These are usually not visible and tend to resolve over time. Following the massage protocol
after the treatment is the most effective way to ensure the product distributes evenly and remains smooth.

● Question: Is it safer than Surgical BBL?
● Answer: Yes, significantly. Surgical BBL carries risks like fat embolism and long recovery times. Lanluma removes these risks completely. It involves no surgery, no
general anesthesia, and zero risk of fat embolism, making it the safest way to enhance your curves.

● Question: Can I sit down after a Butt Lift?

● Answer: Yes! Unlike surgical BBL where you cannot sit for weeks, with Lanluma, there is practically no downtime. Most patients are able to continue their routine
without downtime.

● Question: Does smoking affect the results?
● Answer: Since PLLA relies on your body’s ability to build collagen, smoking (which reduces blood flow) can diminish the results. We recommend reducing smoking
during the treatment period for the best possible outcome.

● Question: What is the price?
● Answer: Pricing is based on the number of vials used. Consultation is required to determine the most appropriate treatment approach

Sculpt Your Body Naturally
To learn more about the power of PLLA and Non-Surgical Contouring, please contact us to schedule a consultation with Specialist Dr. Ömer Fatih Şahin.

HarmonyCa is a breakthrough hybrid injectable that combines Calcium Hydroxyapatite (CaHA) and Hyaluronic Acid (HA) in a single syringe. It provides immediate lifting
while stimulating long-term collagen production. Ideal for patients seeking skin tightening and facial contouring without the overfilled look. Performed by Dr. Ömer Fatih Şahin in Nişantaşı, Istanbul, utilizing advanced vectoring techniques.
What Is HarmonyCa?
HarmonyCa is an innovative hybrid filler developed by Allergan Aesthetics, designed to address aging needs multidimensionally:
● HA (Hyaluronic Acid): Provides immediate moisture, volume, and lifting effect.
● CaHA (Calcium Hydroxyapatite): Bio-stimulating microspheres that trigger natural collagen synthesis over weeks.
This dual-action formula offers instant gratification with sustained biological improvement.
How Does HarmonyCa Work? (The Science)
The treatment works on the skin matrix in two phases:
1. Immediate Lift: The cross-linked HA particles provide an instant lift to the lateral face, improving the jawline and cheek contour immediately after injection.
2. Sustained Bio-stimulation: The CaHA microspheres form a scaffold in the dermis. This stimulates fibroblasts to produce Type 1 Collagen, resulting in firmer, tighter skin starting from week 6–8.
Benefits of HarmonyCa
● Dual Effect: Immediate lifting + Long-term structural improvement.
● Skin Quality: Significantly increases skin elasticity and firmness.
● Lateral Lifting: Effectively tightens the side of the face (cheek to jawline).
● Natural Look: Improves contours without adding excessive bulk or puffiness.
● Longevity: Results can last up to 18–24 months.
Who Is the Ideal Candidate?
HarmonyCa is excellent for individuals engaging in Medical Tourism in Istanbul who want a long-lasting, single-session treatment:
● Men and women aged 30–55 with mild-to-moderate skin laxity.
● Patients noticing sagging in the lateral face or accordion lines on the cheeks.
● Those seeking a collagen boost rather than just simple volume.
● Patients who prefer non-surgical rejuvenation with minimal downtime.
Who Should Avoid It?
● Active autoimmune diseases.
● Active skin infections or inflammation.

● Pregnancy or breastfeeding.
● Patients desiring extreme / sharp jawline projection (High G-prime fillers are better suited for
this specific goal).
Treatment Process in Istanbul
1. Consultation: Detailed facial mapping by Dr. Ömer Fatih Şahin.
2. Preparation: Topical anesthetic is applied for maximum comfort.
3. Procedure: The hybrid filler is injected into the lateral facial vectors using a cannula for safety.
4. Optimization: Manual molding ensures smooth distribution.
5. Timing: The entire procedure takes approximately 20 minutes.
Aftercare Instructions
● Mild swelling or redness for 24–48 hours is normal.
● Avoid strenuous exercise, alcohol, and saunas for the first 24 hours.
● Do not sleep face-down for the first night.
● Results improve over time as collagen production kicks in.
Extended FAQ (11 Questions)
1. How much does HarmonyCa cost in Istanbul? Pricing depends on the number of syringes required for your specific facial structure. Treatment in Turkey is generally more cost-effective than in the UK/EU/USA while maintaining high medical standards. Please contact us for a personalized
quote.
2. How many sessions are needed? Typically, one session is sufficient for visible results. A maintenance treatment may be scheduled after 12–18 months.
3. When will I see results? You will see an immediate lift from the HA component. The skin tightening and quality improvement (from CaHA) become visible after 6–8 weeks.
4. How long do the results last? Clinical data suggests the effects persist for 18 to 24 months.
5. Is HarmonyCa safe? Yes. It uses well-established, biocompatible ingredients (HA and CaHA) with a strong safety profile.
6. Can it be used for the jawline? It is excellent for tightening the jawline skin, but not for creating a sharp, bony jawline projection alone.
7. Is the treatment painful? No. The product contains Lidocaine (an anesthetic), making the injection process very comfortable.
8. Can I combine it with other treatments? Absolutely. It pairs well with Botox, lip fillers, and energy-based devices for total facial rejuvenation.
9. Can HarmonyCa be reversed? The HA component can be dissolved with hyaluronidase. The CaHA component metabolizes naturally over time.
10. Is it suitable for under-eyes? No. Due to the calcium particles, it is not suitable for delicate areas like the tear troughs or lips.
11. Is post-treatment massage required? Your doctor will perform the necessary molding immediately after injection. Routine self-massage is usually not required unless advised.
Planning Your Visit to Istanbul for HarmonyCa
For our international patients visiting Istanbul, HarmonyCa is an ideal lunchtime procedure that allows you to enjoy the city with minimal interruption.
● Recommended Stay: A stay of 2–3 days is sufficient. (Day 1: Arrival & Rest, Day 2: Consultation & Treatment, Day 3: Departure).
● Flying After Treatment: It is generally safe to fly 24 hours after injectable treatments. This allows time for any minor initial swelling to settle.

● Social Downtime: Since there are no surgical bandages or heavy sedation, you can explore the Nişantaşı district—Istanbul’s center for luxury fashion, dining, and art—immediately after
your appointment (while adhering to aftercare rules like avoiding direct sun and saunas).
● Location: Our clinic is located in the heart of Nişantaşı, walking distance from top hotels and luxury shopping malls (City’s Nişantaşı).

The defining advantage of Juvelook is its ability to repair the skin’s collagen architecture from the “inside out,” creating a smooth and refined dermal structure.

Regenerative Pathway: Cellular Induction and Dermal Remodeling

Juvelook’s dual-action technology is designed for deep structural skin renewal:

Hybrid Composition: A precise blend of 5 mg PDLLA (the collagen trigger) and 12.5 mg non-crosslinked HA (for immediate hydration).

Cellular Stimulation: Once injected, Juvelook stimulates fibroblast cells to initiate the production of new collagen (Neocollagenesis).

Biodegradability & Safety: Its micro-particles, sized between 20-40 microns, are gradually broken down into water and carbon dioxide, leaving the body entirely. What remains is a fresh, healthy framework of your own natural collagen fibers.

Why Choose Juvelook for Acne Scars?

While patients often search for “fillers” for acne scars, Juvelook is fundamentally different; it is a scar remodeler.

Atrophic Scar Treatment: For “boxcar” and “rolling” scars caused by collagen loss, Juvelook fills the deficit from within. It physically lifts the base of the scar to level the skin surface.

Enhanced Skin Quality: Scarred tissue is often rigid and lacks elasticity. Juvelook increases dermal density in these areas, restoring the skin’s natural flexibility.

Long-Term Biological Repair: Unlike standard HA fillers that eventually dissolve, the collagen network built by Juvelook becomes part of your own tissue, providing long-lasting structural improvement.

Facial Rejuvenation and the “Glass Skin” Effect

When applied across the entire face, Juvelook optimizes the skin’s general “architecture”:

Pore Minimization: As the collagen matrix strengthens, the diameter of enlarged pores visibly shrinks.

Refined Texture: It eliminates micro-imperfections and “crepey” fine lines, delivering the coveted “Glass Skin”

Natural Aesthetics: Juvelook enhances skin quality and elasticity without altering the natural contours of your face.

Technical Comparison: The Juvelook Difference

Feature

Juvelook (Hybrid PDLLA)

Sculptra/Lanluma (PLLA)

Particle Size

20-40 Microns (Ultra-Fine)

40-80 Microns (Dense)

Massage Protocol

Not Required

Sculptra: 5 Days / Lanluma: 14 Days

Primary Goal

Acne Scars, Texture Quality

Deep Volume & Lifting

Injection Layer

Upper Dermis (Superficial)

Deep Dermis / Subcutaneous

Frequently Asked Questions (FAQ)

Can Juvelook completely remove acne scars?

Juvelook is one of the most effective biological treatments for atrophic (pitted) scars. It significantly reduces scar depth and smooths the skin surface. For optimal results, a protocol of 3 sessions is typically recommended.

Is there a risk of nodules (lumps) after treatment?

Juvelook’s patented spherical molecule structure and high solubility minimize this risk. Unlike older generation polylactic acids, it does not require an aggressive post-treatment massage protocol.

Is Juvelook a dermal filler?

No, it is a biostimulator. While the HA content provides immediate radiance, its primary goal is to stimulate your body to produce its own collagen for long-term repair.

When will I see results and how long do they last?

Hydration and glow are visible shortly after the procedure. However, structural collagen repair begins after the 4th week. The revitalized skin structure usually maintains its resilience and quality for a duration of 1.5 to 2 years.

How many sessions are needed?

For acne scar remodeling and skin texture improvement, a series of 3 sessions spaced 4 weeks apart is the gold standard protocol.

What Are Hip Dips and Why Do They Occur?

Hip dips (also known as violin hips) are inward depressions along the side of your body, just below the hip bone. They are related to the shape of your pelvis, the width of your hips, the position of your femur, and the natural distribution of your fat and muscle.

The most important thing to know is: Hip dips are entirely normal and not a disease.

They are frequently seen in very athletic and slim individuals.

While building gluteal muscle through exercise can slightly soften the appearance, it often cannot completely change the anatomical bone structure.

When evaluating hip dips, the focus should go beyond the simple addition of volume and instead center on the patient’s desired outcome: maximum projection, a softer transition, or improved tissue quality.

What is PLLA (Poly-L-Lactic Acid)?

PLLA is an advanced biostimulator used in aesthetic medicine. Unlike traditional dermal fillers that just take up space, PLLA acts as a “seed” to wake up your body’s fibroblast cells, making them produce fresh collagen.

Lanluma: Officially described as a collagen-stimulating injection that improves skin quality, adds volume, and enhances contours in selected areas. Smoothing out hip dips and enhancing buttocks shape are among its primary body indications.

Sculptra (Galderma): By the end of 2025, Galderma expanded its use in various body areas, including the gluteal region, with EU MDR certification. Galderma emphasizes progressive improvement, skin firmness, lifting effects, and contour optimization.

Why Choose PLLA for Hip Dips? (The Istanbul Approach)

At our clinic in Turkey, we don’t believe in a “one-size-fits-all” approach. However, for many international patients, PLLA-based biostimulation stands out over traditional Hyaluronic Acid (HA) fillers or surgical fat grafting (BBL) for 4 main reasons:

Natural & Gradual Transformation: PLLA avoids the “overfilled” look. It provides natural-looking, progressive results that integrate perfectly with your body.

Skin Quality & Firmness: It’s not just about volume. Sculptra and Lanluma significantly improve skin quality, firmness, and provide a subtle lifting effect to the body.

Non-Surgical (Minimal Downtime): This is crucial for our international patients. Fat grafting requires liposuction, anesthesia, and a long recovery. PLLA injections offer a non-surgical alternative with minimal downtime, allowing you to enjoy your trip to Istanbul.

Biological Support: According to a 2025 expert review, PLLA performs exceptionally well in the gluteal region not by creating massive reshaping, but by providing superior lifting effects and skin quality improvements.

Treatment Comparison: PLLA vs. Fat Grafting

Feature

PLLA (Lanluma / Sculptra)

Surgical Fat Grafting (BBL)

Mechanism

Stimulates your own collagen

Transfers fat from another body part

Procedure Type

Non-surgical (Injections)

Surgical (Requires Liposuction)

Result Timeline

Gradual and progressive

Immediate volume (with initial swelling)

Main Advantage

Natural feel, skin firming, no surgery

Ability to achieve massive volume

The Procedure & What to Expect

Who is the Ideal Candidate?

When Will I See Results?

Results are not instant. The effect develops gradually over time. While volumetric improvement for moderate hip dips is achievable, the biological response in body areas is slower than the face. Peak effects are often seen 3 to 6 months after the initial session.

How Many Sessions Do I Need?