Rejuran Healer is a concentrated form of Polynucleotides (PN) derived from Pacific salmon DNA, which shows high compatibility with human DNA. It is not a filler. When injected into the skin, it acts as a bio-stimulator, repairing damaged tissue from within. Dr. Ömer Fatih Şahin’s Note: “Instead of adding a foreign substance to the skin, Rejuran acts like a project manager, waking up the ‘construction workers’ (fibroblasts) of your skin to start the repair process naturally.”
Mechanism of Action: How It Works
Rejuran Healer triggers four main biological processes:
1. ECM (Extracellular Matrix) Repair: It stabilizes and strengthens the scaffold of the skin.
2. Fibroblast Activation: It stimulates fibroblasts—the fountain of youth cells—to increase Type I and Type III collagen production.
3. Anti-Inflammatory Effect: It suppresses micro-inflammation in the skin, reducing redness and sensitivity.

4. Angiogenesis (Circulation Support): It regulates microcirculation, improving skin oxygenation and glow.
Comparative Analysis: Rejuran Healer or Dermal Fillers?
The most frequent question we hear is: “Doctor, is this a filler? Will it make my face puffy?” No, Rejuran Healer is not a filler. Here are the distinctions:
● Primary Goal: Fillers aim to fill voids and add volume. Rejuran Healer aims to improve skin quality and repair damage.
● Fillers can make areas look fuller. Rejuran Healer does not plump the face; it works on improving skin quality instead.
● Target Tissue: Fillers are often placed deep (on bone or fat pads). Rejuran is injected into the Dermis (the skin layer).
● Result Timeline: Fillers show instant results. Rejuran results appear gradually over 3-4 weeks as biological repair occurs.
● Look: Fillers provide contour. Rejuran provides tighter, smoother, and more radiant skin texture.
Functional Medicine & Holistic Approach
At our clinic, we don’t view Rejuran Healer merely as an injection. Skin quality is directly linked to gut health, sleep patterns, and stress levels.
We evaluate factors such as:
● Stress Management: High cortisol accelerates collagen breakdown.
● Nutrition: Sugar and processed foods age the skin via “Glycation.”
● Micronutrient Support: We ensure optimal vitamin/mineral balance to boost the effects of Rejuran.
Our goal is not temporary shine, but a biologically healthier and more resilient tissue environment.
Who Is It Suitable For? (Indications)
This protocol is ideal for individuals with:
● Skin that has lost elasticity and is prone to sagging.
● Enlarged pores and sebum (oil) imbalance.
● Acne scars (atrophic scars) and uneven skin texture.
● Dull, dehydrated, and “tired-looking” skin.
● Fine wrinkles starting to appear (especially on the neck and cheeks).
Frequently Asked Questions (FAQ)
Will Rejuran Healer change my face shape? No. Since it is not a filler, it does not alter your facial features or create puffiness. It simply improves the texture and youthfulness of your skin.
Is the procedure painful? The treatment involves micro-injections. Thanks to Dr. Ömer Fatih Şahin’s Anesthesiology background, pain management and patient comfort are maximized through special pre-procedure protocols.
Can it be done in summer? Yes. Rejuran does not cause photosensitivity (sun sensitivity). On the contrary, because it strengthens the skin barrier, it is a safe and excellent choice before or after summer to repair sun damage.