Profhilo is an award-winning, injectable anti-aging treatment made from ultra-pure Hyaluronic Acid. It is not a filler; it is a Bio-Remodeling agent that stimulates collagen and elastin to tighten sagging skin. At our Nişantaşı, Istanbul clinic, we use the specialized BAP (5-Point) Technique for maximum results with minimal downtime.
What Is Profhilo? (Injectable Skincare)
Think of Profhilo as a super-powerful moisturizer that works from the inside out. It contains one of the highest concentrations of Hyaluronic Acid on the market (64mg), stabilized without chemical cross-linking agents (BDDE-free) using patented NAHYCO® Technology.
The Result: It spreads like honey under the skin, treating the entire face rather than just filling a specific line.
How Does It Work?
Profhilo does not just hydrate; it remodels the aging tissue.

1. Stimulates: It wakes up your skin cells (fibroblasts) to produce 4 different types of Collagen and Elastin.
2. Tightens: It improves skin laxity (sagging) on the face, neck, and body.
3. Hydrates: It attracts water to the deep layers of the skin, creating a “dewy” look.
The Procedure: BAP Technique (5 Points)
We use the Bio Aesthetic Points (BAP) technique. Instead of multiple injections all over the face, we
inject specific boluses into 5 strategic points on each side of the face.
● Why? These points ensure the product spreads evenly across the entire face, minimizing
pain and the risk of bruising.
Who Is It For?
● Anyone noticing skin laxity (sagging) or dullness.
● Patients who want to avoid the “puffy” look of dermal fillers.
● Ideal for treating difficult areas like the Neck, Hands, and Arms.
● Suitable for all ages (prevention in 30s, repair in 40s+).
Treatment Protocol
1. Sessions: 2 sessions are recommended, spaced 4 weeks apart.
2. Maintenance: Results last for 6–9 months. A single maintenance session is recommended every
6 months to keep the “glow.”
Frequently Asked Questions
1. Is Profhilo a Filler? No. Fillers stay where they are injected to add volume and change facial
shape. Profhilo spreads under the skin to improve skin quality and tightness. It will not make your
face look puffy or round.
2. Is it painful? It is very comfortable compared to traditional mesotherapy. We use the BAP
(5-Point) Technique, meaning only 5 injection points per side. With numbing cream, discomfort is
minimal.
3. What is the best age to start?
● In your 30s: It acts as preventative care, maintaining the skin’s glow and collagen levels.
● In your 40s and beyond: It acts as a corrective treatment, tightening sagging skin and
restoring elasticity.
4. What is Profhilo Structura? It is a specialized version designed to support the superficial fat
pads of the face. It provides a “Lipolifting” effect, ideal for patients with hollow cheeks or more
advanced sagging. We will choose the best version for you during consultation.
5. Can it treat the Neck and Hands? Yes. Profhilo is considered the gold standard for treating
horizontal neck lines (“Tech Neck”) and rejuvenating the thin skin on the back of the hands.
6. Is there any downtime? Minimal. You may have small bumps (like mosquito bites) at the injection
points, which usually disappear within 12–24 hours as the product spreads underneath the skin. You
can return to work immediately.
7. Can I combine it with Botox? Yes. Botox relaxes dynamic wrinkles, while Profhilo improves the
overall skin texture. They work perfectly together for a complete rejuvenation.
8. Is it safe? Yes. Profhilo uses ultra-pure Hyaluronic Acid without chemical cross-linking agents
(BDDE-free), making it highly biocompatible with a very low risk of adverse reactions.
9. What is the cost in Istanbul? Prices depend on the area treated (Face, Neck, Body) and the
number of sessions. Treatment in Turkiye offers premium European quality at a competitive price.